Novel santalane sesquiterpenoids from the stem bark of Duguetia glabriuscula - Annonaceae

• Author(s): Pereira, Núbia F. Gomes ; Carollo, Carlos Alexandre ; Garcez, Walmir Silva ; Siqueira, João Máximo de
• Date: 2011
• Origin: Oasisbr
• Subject(s): Annonaceae; Duguetia Glabriuscula; Santalane Sesquiterpenes
• Document Type: Journal article
• Language: English

Description

Five novel santalane-type sesquiterpenes were isolated from the stem bark of Duguetia glabriuscula – Annonaceae. Their structures have been established on the basis of spectral data and chemical evidences (1H and 13C NMR, HMQC, HMBC) as (+)-a-santal-10-en-9-ol (1), (+)-a-santalan-10,11-epoxy-9-ol (2), a-santal-11-en-9,10-diol (3), (+)-a-santalan-9,10,11-triol (4), and (+)-a-santalan-9,11-epoxy-10-ol (5). Polycarpol, a triterpenoid, was also obtained.