Novos constituintes químicos das cascas do caule de Tabebuia heptaphylla

• Author(s): Garcez, Fernanda Rodrigues ; Garcez, Walmir Silva ; Mahmoud, Talal Suleiman ; Figueiredo, Patrícia de Oliveira ; Resende, Ubirazilda Maria
• Date: 2011
• Origin: Oasisbr
• Subject(s): Tabebuia; Triterpenos; Iridóides; Triterpenes; Iridoids
• Document Type: Journal article
• Language: Portuguese

Description

new triterpene, 3b,6b,21b-trihydroxyolean-12-ene and a new iridoid, 8a-methyl-8b-hydroxy-6b-(3',4'-dimethoxy)benzoyloxy-1 a,3a-dimethoxy-octahydro-cyclopenta[c]pyran were isolated from the trunk bark of a specimen of Tabebuia heptaphylla (Bignoniaceae) collected in the "Pantanal" of Mato Grosso do Sul, Brazil. Twelve known compounds were also obtained in this work, comprising four iridoids, 6-O-p-hydroxybenzoylajugol, 6-O-p-methoxybenzoylajugol, 6-O-3",4"-dimethoxybenzoylajugol, 8a-methyl-8b-hydroxy-6b-(4'-hydroxy)benzoyloxy-1a,3 a-dimethoxy-octahydro-cyclopenta[c]pyran, a cyclopentene dialdehyde, 2-formyl-5-(3',4'-dimethoxybenzoyloxy)-3-methyl-2-cyclopentene-1-acetaldehyde, a phenylethanoid glycoside, verbascoside and three benzoic acid derivatives, p-hydroxybenzoic, p-methoxybenzoic and 3,4-dimethoxybenzoic acids, in addition to squalene, sitostenone and sitosterol. The antioxidant properties of the isolated compounds were also evaluated in this work.