Autor(es): Solon, Soraya ; Carollo, Carlos Alexandre ; Brandão, Luiz Fabrício Gardini ; Macedo, Cristiana dos Santos de ; Klein, André ; Dias-Junior, Carlos Alan ; Siqueira, João Máximo de
Data: 2014
Origem: Oasisbr
Assunto(s): Produtos com Ação Antimicrobiana; Acetatos; Fenol; Products with Antimicrobial Action; Acetates; Phenol
ABSTRACT - This study describes the chemical investigation of the ethyl acetate fraction obtained from the hydroethanolic extract of the xylopodium of Cochlospermum regium (Mart. & Schr.) Pilger, which has been associated with antimicrobial activity. Phytochemical investigation produced seven phenol derivatives: ellagic acid, gallic acid, dihydrokaempferol, dihydrokaempferol-3-O-β-glucopyranoside, dihydrokaempferol-3-O-β-(6"-galloyl)-glucopyranoside, pinoresinol, and excelsin. It also contained two triacylbenzenes, known as cochlospermines A and B. The hydroethanolic extract and its fractions exhibited antimicrobial activity (0.1 mg/mL) against Staphylococcus aureus and Pseudomonas aeruginosa. Gallic acid showed activity against S. aureus. Dihydrokaempferol-3-O-β-(6"-galloyl)-glucopyranoside is reported here for the first time in the literature.
