Valproyl-dephosphocoa

• Author(s): Silva, MFB ; Ijlst, L ; Allers, P ; Jakobs, C ; Duran, M ; de Almeida, IT ; Wanders, RJA
• Date: 2004
• Persistent ID: http://hdl.handle.net/10451/21334
• Origin: Repositório da Universidade de Lisboa
• Subject(s): Pharmacology & Pharmacy
• Document Type: Journal article
• Language: English
• Contributor(s): Repositório Científico de Acesso Aberto da ULisboa

Description

The mitochondrial metabolism of valproic acid (VPA) was investigated in vitro to elucidate its beta-oxidation pathway since the characterization of VPA intermediates in the acyl-CoA thioester form, and not just in their free acid form, has not been fully