Author(s):
Souza, Renato T. ; Costa, Maria L. ; Mayrink, Jussara ; Feitosa, Francisco E. ; Rocha Filho, Edilberto A. ; Leite, Débora F. ; Vettorazzi, Janete ; Calderon, Iracema M. [UNESP] ; Sousa, Maria H. ; Passini, Renato ; Baker, Philip N. ; Kenny, Louise ; Cecatti, Jose G. ; Parpinelli, Mary A. ; Fernandes, Karayna G. ; Galvão, Rafael B. ; Guida, José Paulo ; Santana, Danielly S. ; de Lucena, Daisy ; Sousa, Benedita ; Melo, Elias F. ; Anacleto, Danilo ; Pfitscher, Lucia ; Brust, Luiza ; Cassettari, Bianca F. [UNESP] ; Franchini, Kleber G. ; Pacagnella, Rodolfo C.
Date: 2020
Persistent ID: http://hdl.handle.net/11449/200507
Origin: Oasisbr
Description
Made available in DSpace on 2020-12-12T02:08:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-01
Preterm birth is the major contributor for neonatal and under-five years mortality rates and also accounts for a short- and long-term adverse consequences up to adulthood. Perinatal outcomes may vary according to lots of factors as preterm subtype, late prematurity, which account for the vast majority of cases, country and population characteristics. An under-recognition of the perinatal outcomes and its associated factors might have underpowered strategies to provide adequate care and prevent its occurrence. We aim to estimate the frequency of maternal and perinatal outcomes in women with different categories of preterm and term births, factors associated with poorer perinatal outcomes and related management interventions. A multicentre prospective cohort in five maternities in Brazil between 2015 and 2018. Nulliparous low-risk women with singletons were included. Comprehensive data were collected during three antenatal visits (at 19–21weeks, 27–29 weeks and 37–39 weeks). Maternal and perinatal outcomes were also collected according to maternal and neonatal medical records. Women who had spontaneous (sPTB) and provider-initiated (pi-PTB) preterm birth were compared to those who had term birth. Also, late preterm birth (after 34 weeks), and early term (37–38 weeks) were compared to full term birth (39–40 weeks). Bivariate analysis estimated risk ratios for maternal and adverse outcomes. Finally, a multivariate analysis was conducted to address factors independently associated with any adverse perinatal outcome (APO). In total, 1,165 women had outcome data available, from which 6.7% had sPTB, 4.0% had pi-PTB and 89.3% had a term birth. sPTB and pi-PTb were associated with poorer perinatal outcomes, as well as late sPTB, late pi-PTB and early term neonates. pi-PTB (RRadj 8.12, 95% CI [2.54–25.93], p-value 0.007), maternal weight gain between 20 and 27 weeks
Department of Obstetrics and Gynaecology University of Campinas (UNICAMP) School of Medical Sciences
MEAC – School Maternity of the Federal University of Ceará
Department of Maternal and Child Health Maternity of Clinic Hospital Federal University of Pernambuco
Department of Obstetrics and Gynaecology Maternity of the Clinic Hospital Federal University of RS
Department of Obstetrics and Gynaecology Botucatu Medical School Unesp
Statistics Unit Jundiai School of Medicine
College of Life Sciences University of Leicester
Faculty of Health and Life Sciences University of Liverpool
LNBio - Brazilian Biosciences National Laboratory and School of Medical Sciences University of Campinas (UNICAMP)
Department of Obstetrics and Gynaecology Botucatu Medical School Unesp
