Autor(es): Guido, Rafael V.C. [UNESP] ; Andricopulo, Adriano D. ; Oliva, Glaucius
Data: 2022
Identificador Persistente: http://hdl.handle.net/11449/219615
Origem: Oasisbr
Assunto(s): Drug design; Enzymes; Infectious diseases; Inhibitors; Medicinal chemistry; Molecular modeling
Made available in DSpace on 2022-04-28T18:56:36Z (GMT). No. of bitstreams: 0 Previous issue date: 2010-12-21
Current drug design strategies are based on the understanding of the physiopathology of diseases, biochemical pathways and selection of molecular targets. Modern biotechnological tools have provided valuable information to facilitate the discovery of new drug candidates. Medicinal chemistry has a vital role in a variety of processes aimed at the identification of bioactive substances and the development of lead-compounds with optimized pharmacodynamic and pharmacokinetic properties. The present paper presents some fundamental aspects of biotechnology and medicinal chemistry as useful tools in the design of new chemical entities for the therapy of infectious diseases.
Universidade Estadual Paulista Júlio de Mesquita Filho (Unesp) Instituto de Física de São Carlos (IFSC-USP)
Universidade Federal de Santa Maria (UFSM) Universidade de Michigan Instituto de Física de São Carlos (IFSC-USP)
Instituto de Física e Química de São Carlos (IFQSC-USP) Instituto de Física de São Carlos Institutos Nacionais de Ciência e Tecnologia (INCT)
Universidade Estadual Paulista Júlio de Mesquita Filho (Unesp) Instituto de Física de São Carlos (IFSC-USP)
