Author(s):
Sannomiya, Miriam [UNESP] ; Michelin, D. C. [UNESP] ; Rodrigues, C. M. [UNESP] ; Santos, Lourdes Campaner dos [UNESP] ; Salgado, H. R N [UNESP] ; Hiruma-Lima, C. A. ; Brito, A. R S M ; Vilegas, Wagner [UNESP]
Date: 2014
Persistent ID: http://hdl.handle.net/11449/68638
Origin: Oasisbr
Subject(s): Antimicrobial activity; Byrsonima crassa; Malpighiaceae; Byrsonima crassa extract; epigallocatechin gallate; gallic acid methyl ester; methanol; plant extract; pyranoside; quercetin; quercitin 3 o (2'' galloyl) alpha levo arabinopyranoside; unclassified drug; antimicrobial activity; drug activity; drug mechanism; high performance liquid chromatography; in vitro study; medicinal plant; nonhuman
Description
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The methanolic extract of leaves from Byrsonima crassa, a Brazilian medicinal plant, was analyzed by CC and HPLC. Four constituents were isolated and identified as quercetin, methyl gallate, (-)-epigallocatechin gallate and quercetin-3-O-(2″-galloyl)-α-L-arabinopyranoside. The methanolic and hydromethanolic extract, as well as fractions, were evaluated regarding their possible antimicrobial activity using in vitro methods. Results showed that both extracts and fractions exhibited significant antimicrobial activity against all tested strains.
Departamento de Química Orgânica Instituto de Química Universidade Estadual Paulista, Araraquara - SP
Departamento de Fármacos e Medicamentos Faculdade de Ciências Farmacêuticas Universidade Estadual Paulista, 14800-901, Araraquara - SP
Departamento de Fisiologia Instituto de Biociências, 18618-000 UNESP, Botucatu, SP
Departamento de Fisiologia e Biofísica Instituto de Biologia UNICAMP, 13083-970, Campinas, SP
Departamento de Química Orgânica Instituto de Química UNESP, Rua Prof. Francisco Degni s/n, 14801-970, Araraquara, SP
Departamento de Química Orgânica Instituto de Química Universidade Estadual Paulista, Araraquara - SP
Departamento de Fármacos e Medicamentos Faculdade de Ciências Farmacêuticas Universidade Estadual Paulista, 14800-901, Araraquara - SP
Departamento de Química Orgânica Instituto de Química UNESP, Rua Prof. Francisco Degni s/n, 14801-970, Araraquara, SP
