Document details

Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines

Author(s): Guimarães, Bárbara S. G. ; Sousa, Maria João ; Gonçalves, M. Sameiro T.

Date: 2024

Persistent ID: https://hdl.handle.net/1822/94805

Origin: RepositóriUM - Universidade do Minho

Project/scholarship: info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00686%2F2020/PT;

Subject(s): benzo[a]phenoxazines; Nile Blue derivatives; fluorescent probes; Saccharomyces cerevisiae


Description

The synthesis and full characterization of new hydroxyl benzo[a]phenoxazinium chlorides with N-(di)propyl and/or N-isopropyl groups in the 5 and 9 positions are described. Photophysical studies carried out in ethanol and water revealed strong absorbances and significant fluorescence emissions at up to 676 nm. The antifungal activity was assessed against Saccharomyces cerevisiae and the results provide possible directions for further studies.

This research was funded by Fundação para a Ciência e Tecnologia (FCT) Portugal, by the strategic programmes UID/QUI/0686/2020. Thanks are also due to FCT for financial support to the Portuguese NMR network (PTNMR, Bruker Avance III 400-Univ. Minho).

Document Type Conference paper
Language English
Contributor(s) Universidade do Minho
CC Licence
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