Autor(es): Guimarães, Bárbara S. G. ; Sousa, Maria João ; Gonçalves, M. Sameiro T.
Data: 2024
Identificador Persistente: https://hdl.handle.net/1822/94805
Origem: RepositóriUM - Universidade do Minho
Projeto/bolsa: info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F00686%2F2020/PT;
Assunto(s): benzo[a]phenoxazines; Nile Blue derivatives; fluorescent probes; Saccharomyces cerevisiae
The synthesis and full characterization of new hydroxyl benzo[a]phenoxazinium chlorides with N-(di)propyl and/or N-isopropyl groups in the 5 and 9 positions are described. Photophysical studies carried out in ethanol and water revealed strong absorbances and significant fluorescence emissions at up to 676 nm. The antifungal activity was assessed against Saccharomyces cerevisiae and the results provide possible directions for further studies.
This research was funded by Fundação para a Ciência e Tecnologia (FCT) Portugal, by the strategic programmes UID/QUI/0686/2020. Thanks are also due to FCT for financial support to the Portuguese NMR network (PTNMR, Bruker Avance III 400-Univ. Minho).
