Author(s): Yassue-Cordeiro, Patrícia Hissae ; Severino, Patrícia ; Souto, Eliana B. ; Yoshida, Cristiana Maria Pedroso ; Silva, Classius Ferreira da
Date: 2019
Persistent ID: https://hdl.handle.net/1822/61686
Origin: RepositóriUM - Universidade do Minho
Subject(s): Commercial dressings; Drug delivery; Fluid handling capacity; Healing activity; Natural polysaccharide; Semisynthetic polysaccharide; Wound dressings
This chapter discusses one innovative pharmaceutical form: the so-called two-dimensional system or flat system. They can be subdivided into films (or membranes), or even fabrics. The main applications of these systems are in the development of controlled release formulations, wound dressings, and in tissue engineering. This chapter focuses on the wound dressings for healing. A brief conceptualization and introduction on the main characteristics of these systems are presented, as well as an overview of the products available in the world market and the methods of preparation of the dressings. The materials used to produce these systems may be of synthetic or of natural sources, such as natural polysaccharides or semisynthetic polysaccharides. Two of the main properties of dressings are fluid-handling capacity and wound healing. An overview of publications on natural polysaccharidesbased dressings is presented. Finally, the leading mathematical models for the release of active compounds from flat systems are introduced.
