Author(s):
Handels, Ron ; Hataiyusuk, Somboon ; Wimo, Anders ; Sköldunger, Anders ; Bakker, Christian ; Bieber, Anja ; Ciccone, Alfonso ; Defanti, Carlo Alberto ; Fabbo, Andrea ; Fascendini, Sara ; Frölich, Lutz ; Gervès-Pinquié, Chloé ; Gonçalves-Pereira, M. ; Irving, Kate ; Koopmans, Raymond ; Mecocci, Patrizia ; Merlo, Paola ; Michalowsky, Bernhard ; Peters, Oliver ; Pijnenburg, Yolande ; Ribeiro, Óscar ; Salbaek, Geir ; Schwarzkopf, Larissa ; Verbeek, Hilde ; de Vugt, Marjolein ; Woods, Bob ; Zanetti, Orazio ; Winblad, Bengt ; Jönsson, Linus
Date: 2025
Persistent ID: http://hdl.handle.net/10362/178776
Origin: Repositório Institucional da UNL
Subject(s): costs; Dementia; health-economic evaluation; informal care; resource use; Clinical Neurology; Psychiatry and Mental health; SDG 3 - Good Health and Well-being
Description
Publisher Copyright: Copyright © 2024 The Author(s). Published by Elsevier Masson SAS.. All rights reserved.
INTRODUCTION: Informal care estimates for use in health-economic models are lacking. We aimed to estimate the association between informal care time and dementia symptoms across Europe. METHODS: A secondary analysis was performed on 13,529 observations in 5,369 persons from 9 European pooled cohort or trial studies in community-dwelling persons with dementia. A mixed regression model was fitted to time spent on instrumental or basic activities of daily living using disease severity and demographic characteristics. RESULTS: Daily informal care time was 0.5 hours higher in moderate compared to mild and 1.3h higher in severe compared to mild cognitive impairment. Likewise, this was 1.2h and 2.7h for functional disability and 0.3h and 0.6h for behavioral symptoms in the same directions. DISCUSSION: Estimates can be used in both single- and multi-domain health-economic models for dementia in European settings.
