Autor(es): Carrete Junior,Henrique ; Abdala,Nitamar ; Lin,Kátia ; Caboclo,Luís Otávio ; Centeno,Ricardo Silva ; Sakamoto,Américo Ceiki ; Szjenfeld,Jacob ; Nogueira,Roberto Gomes ; Yacubian,Elza Márcia Targas
Data: 2007
Origem: Oasisbr
Assunto(s): epilepsy; temporal lobe epilepsy; hippocampal sclerosis; temporal pole; magnetic resonance imaging
OBJECTIVE: To determine the frequency and regional involvement of temporal pole signal abnormality (TPA) in patients with hippocampal sclerosis (HS) using fluid-attenuated inversion-recovery (FLAIR) MR imaging, and to correlate this feature with history. METHOD: Coronal FLAIR images of the temporal pole were assessed in 120 patients with HS and in 30 normal subjects, to evaluate gray-white matter demarcation. RESULTS: Ninety (75%) of 120 patients had associated TPA. The HS side made difference regarding the presence of TPA, with a left side prevalence (p=0.04, chi2 test). The anteromedial zone of temporal pole was affected in 27 (30%) out of 90 patients. In 63 (70%) patients the lateral zone were also affected. Patients with TPA were younger at seizure onset (p=0.018), but without association with duration of epilepsy. CONCLUSION: Our FLAIR study show temporal pole signal abnormality in 3/4 of patients with HS, mainly seen on the anteromedial region, with a larger prevalence when the left hippocampus was involved.
