Author(s): Silva,Aída Cristina do Nascimento ; Ferrazoli,Lucilaine ; Simonsen,Vera ; Reis,Joice Neves ; Pereira,Susan Martins ; Carmo,Theomira Mauadie de Azevedo ; Mota,Eduardo Luiz Andrade ; Reis,Mitermayer Galvão
Date: 2011
Origin: Oasisbr
Subject(s): Tuberculosis; Molecular Epidemiology; Genetic Variation; Mycobacterium tuberculosis
This study constitutes a first attempt to describe the genetic population structure of Mycobacterium tuberculosis circulating in Salvador, Bahia State, Brazil. A total of 56 confirmed cases of pulmonary tuberculosis, identified between March and June 2008, were analyzed using restriction fragment length polymorphism (IS6110-RFLP). The study population was characterized by a predominance of males (71.43%) over 30 years of age (68.75%). Forty-one isolates were found to belong to a single pattern (73.2%), while 15 (26.7%) were found in group patterns, forming six clusters. The higher level of diversity observed is much more suggestive of endogenous reactivation than recent transmission.
