blaGES carrying Pseudomonas aeruginosa isolates from a public hospital in Rio de Janeiro, Brazil

• Autor(es): Pellegrino,Flávia L. P. C. ; Netto-dos Santos,Kátia R. ; Riley,Lee W. ; Moreira,Beatriz M.
• Data: 2006
• Origem: Oasisbr
• Assunto(s): Pseudomonas aeruginosa; blaGES, antibiotics; public hospital; Rio de Janeiro; Brazil
• Tipo de Documento: Artigo científico
• Idioma: Inglês

Descrição

Previous analysis of Pseudomonas aeruginosa class-1 integrons from Rio de Janeiro, Brazil, revealed the blaGES gene in one isolate. We screened isolates of two widespread PFGE genotypes, A and B, at a public hospital in Rio, for the presence of blaGES. The gene was detected in all seven P. aeruginosa isolates belonging to genotype B. Three of the seven genotype-B isolates were resistant to amikacin, aztreonam, ceftazidime, cefepime, ciprofloxacin, gentamicin, imipenem, meropenem, piperacillin-tazobactam and ticarcillin-clavulanic acid. The other four isolates were resistant to all these agents, except gentamicin, imipenem, meropenem and piperacillin-tazobactam. A synergistic effect between ceftazidime and imipenem or clavulanic acid suggested the production of GES-type ESBL.