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Carcinoma Adenóide Cístico: Uma Causa Rara de Obstrução da Traqueia

Silva Martins, Ricardo; Rodrigues, Susana; Freixo, Beatriz; Bacelar, Maria Teresa; Lapa, Alexandra; Coimbra, Nuno; Fonseca, Diogo

O carcinoma adenóide cístico (CAC) da traqueia é uma neoplasia maligna rara, pouco consensual na literatura em relação ao estadiamento e abordagem terapêutica. Dada a sua raridade, é por vezes difícil o diagnóstico correto com os achados clínicos e imagiológicos, o que condiciona frequentemente atraso no diagnóstico. A familiarização do radiologista com esta entidade é fundamental para a sua deteção precoce e i...

Date: 2023   |   Origin: Acta Radiológica Portuguesa

Impact of high‐risk human papilloma virus genotyping in cervical disease in the...

Rosário, Andreia; Sousa, Ana Saraiva; Marinho-Dias, Joana; Medeiros, Rui; Lobo, Cláudia; Leça, Luís; Coimbra, Nuno; Tavares, Fernando; Baldaque, Inês

Cervical cancer prevention is based on primary prevention with vaccines againstHuman Papillomavirus (HPV) and secondary prevention by screening with High‐Risk‐HPV (Hr‐HPV) detection. Since 2017, cervical cancer screening in women aged25−60 years has been performed in Portugal using Hr‐HPV detection, followed bycytology in Hr‐HPV‐positive cases. Herein we report the prevalence of Hr‐HPVgenotypes and cytological ...

Date: 2023   |   Origin: Biblioteca Digital do IPB

Do we still need axillary staging in the context of mastectomy after at least o...

Ribeiro, Cátia; Antunes, Pedro; Mesquita, Ana; Martins, Pedro; Peyriteo, Mariana; Sousa, Alexandre; Coimbra, Nuno; Leal, Conceição

Goals: Sentinel lymph node biopsy (SLNB) is indicated when a mastectomy is performed by Ductal Carcinoma In Situ (DCIS). When mastectomy is performed after one or more attempts of breast conservative surgery (BCS), the need to perform SLNBis questionable. The goal of this study was to determine the histological upgrade rate and SLNB results in this specific group of patients.Methods: Retrospective study of a ca...


Comprehensive metabolomics and lipidomics profiling of prostate cancer tissue r...

Lima, Ana Rita; Carvalho, Márcia; Aveiro, Susana; Melo, Tânia; Domingues, M. Rosário; Macedo-Silva, Catarina; Coimbra, Nuno; Jerónimo, Carmen

Prostate cancer (PCa) is a global health problem that affects millions of men every year. In the past decade, metabolomics and related subareas, such as lipidomics, have demonstrated an enormous potential to identify novel mechanisms underlying PCa development and progression, providing a good basis for the development of new and more effective therapies and diagnostics. In this study, a multiplatform metabolom...


Vaginal Metastasis from Colorectal Adenocarcinoma: Diagnosis in Cervicovaginal ...

Mendes, Marta Daniela Valente; Oliveira, Beatriz; Cunha, Celina; Coimbra, Nuno; Duarte, Anabela; Babo, Armanda; Martins, Conceição; Monteiro, Paula

Metastatic colorectal adenocarcinoma in the vagina is rare and there are few reported cases in the literature. This paper reports a case of a woman with an infiltrative mass in the vagina and a previous diagnosis of colorectal adenocarcinoma. The use of cervicovaginal liquid based cytology together with CK20 and CDX2 immunostaining allowed to confirm the neoplasia’s colorectal origin. This case enhanced the imp...

Date: 2016   |   Origin: Citotech Online - Case Review

Metástase vaginal deadenocarcinoma colorretal: Diagnóstico em citologia cérvico...

Mendes, Marta Daniela Valente; Oliveira, Beatriz; Cunha, Celina; Coimbra, Nuno; Duarte, Anabela; Babo, Armanda; Martins, Conceição; Monteiro, Paula

O adenocarcinoma colorretal metastático na vagina é raro e são poucos os casos descritos na literatura. O presente trabalho relata o caso de uma mulher com uma massa infiltrativa na vagina e um diagnóstico prévio de adenocarcinoma colorretal. A utilização da citologia cérvico-vaginal em meio líquido em conjunto com os marcadores imunohistoquímicos CK20 e CDX2 permitiu confirmar a origem colorretal da neoplasia....


Factors Affecting Macroinvertebrate Richness and Diversity in Portuguese Stream...

Graça, Manuel A. S.; Pinto, Paulo; Cortes, Rui; Coimbra, Nuno; Oliveira, Simone; Morais, Manuela; Carvalho, Maria João; Malo, Jorge

We analysed the spatial patterns in macroinvertebrate taxon richness and abundance at two scales: sampling unit and basin. We sampled 12 stream sites in three zones of Portugal, differing in climate geomorphology and water chemistry. At a sampling unit scale, substratum organic matter content, depth and the dominant size of substratum particles were correlated with numbers of taxa and individuals. We propose th...


Factors Affecting Macroinvertebrate Richness and Diversity in Portuguese Stream...

Graça, Manuel A. S.; Pinto, Paulo; Cortes, Rui V.; Coimbra, Nuno; Oliveira, Simone; Morais, Manuela; Carvalho, Maria João; Malo, Jorge

Date: 2004   |   Origin: Repositório da UTAD

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