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DIAGNOSTIC - challeng

Nunes, Filipa; Bastos, Martim; Costa, Mariana; Oliveira, Jéssica; Dutschmann, Rita

Neste caso, a marcha diagnóstica consistiu na exclusão de causa neoplásica com a realização de TC de corpo, toracocentese e exames endoscópicos A biópsia do duodeno foi primordial para estabelecer o diagnóstico atempado de Doença de Whipple com identificação do bacilo Tropheryma whipplei


Secular Trends in the Mortality by Cerebrovascular Diseases in Portugal: 1902-2012

Pinhão Ramalheira, Carlos; M. Gonçalves, Ana; Gomes, Filipa; Dutschmann, Rita; Gusmão, Ricardo

Introduction: Cerebrovascular diseases (CVD) are one of the main causes of death in Portugal. Research on the epi- demiologic history might help to understand the phenomenon and guide intervention strategies. Objectives: (1) Describe historic trends in mortality. (2) Estimate the impact of demographic variations on the registered number of cases. Methods: (1) We calculated rates, specific and standard- ized, fo...


A Rare Iatrogenic Reaction to Allopurinol

Carvalho e Branco, Joana; Gomes, A. Filipa; Dutschmann, Rita; Dutschmann, Luís

There are very few case reports of iatrogenic bone marrow granuloma induced by allopurinol. Granulomas are a rare finding on bone marrow biopsies and can have numerous etiologies, namely infectious, neoplastic, autoimmune, drug related or sarcoidosis. In the absence of pathognomonic features, the combination of clinical, laboratorial, image and histological data is essential to establish a diagnosis. We report ...


Left supraclavicular lymph node enlargement as the initial manifestation of met...

Dutschmann, Rita; Nunes da Silva, Maria João; Pires, Carlos; Costa, Luís; Lucas, Margarida; M. M. Vitorino, Rui

The involvement of supraclavicular lymph nodes in metastatic prostate cancer is usually considered uncommon, and is extremely rare as the initial manifestation of the disease. We describe the clinical case of a 77 year-old man, who presented with left supraclavicular lymphadenopathy for 3 months, with no other symptoms. The investigation led to the diagnosis of prostate cancer with metastatic ganglionar dissemi...


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