Author(s): Boazinha, João Pedro ; Carneiro, João ; Cerqueira, Nuno M. F. S. A. ; Sousa, Sérgio F.
Date: 2026
Persistent ID: http://hdl.handle.net/10400.14/58760
Origin: Veritati - Repositório Institucional da Universidade Católica Portuguesa
Document details
AI-assisted and physics-refined modeling of human voltage-gated sodium channels for selective target discovery
Description
Introduction: Voltage-gated sodium channels are membrane proteins that open and close in response to voltage changes to allow Na⁺ influx in excitable cells, enabling action potentials, muscle contraction, and electrical signaling. Aim: Apply a hybrid modelling strategy that combines artificial intelligence and physics-based refinement to build a realistic 3D models of NaV channels.
Document Type
Conference poster not in proceedings
Language English
Contributor(s) Veritati
Language English
Contributor(s) Veritati
