Author(s): Bragato, Jaqueline Poleto [UNESP] ; Melo, Larissa Martins [UNESP] ; Venturin, Gabriela Lovizutto [UNESP] ; Rebech, Gabriela Torres [UNESP] ; Garcia, Leandro Encarnação [UNESP] ; Lopes, Flavia Lombardi [UNESP] ; de Lima, Valéria Marçal Felix [UNESP]
Date: 2018
Persistent ID: http://hdl.handle.net/11449/170630
Origin: Oasisbr
Subject(s): Dog; Leishmania infantum; miRNA; Dog; Dog; Leishmania infantum; Leishmania infantum; miRNA; miRNA
Made available in DSpace on 2018-12-11T16:51:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-04-01
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
This paper contains data on differentially expressed miRNAs in peripheral blood mononuclear cells (PBMC) of dogs naturally infected by Leishmania (L.) infantum compared to healthy dogs. In recent years, studies with miRNAs have shown that these molecules play a critical role in the regulation and function of immune response.Differentially expressed miRNAs were identified by microarray, validated by real time PCR and compared with parasite load in the dogs. Targets and pathways were analyzed using the Ingenuity Pathway Analysis program.
Department of Animal Clinic Surgery and Reproduction São Paulo State University (Unesp) School of Veterinary Medicine
Department of Support Production and Animal Health São Paulo State University (Unesp) School of Veterinary Medicine
Department of Animal Clinic Surgery and Reproduction São Paulo State University (Unesp) School of Veterinary Medicine
Department of Support Production and Animal Health São Paulo State University (Unesp) School of Veterinary Medicine
FAPESP: 2015/16972-7
FAPESP: 2016/02359-4
