Autor(es): Rodrigues, Diego S. ; Mancera, Paulo F.A. [UNESP] ; Carvalho, Tiago ; Gonçalves, Luiz Fernando [UNESP]
Data: 2020
Identificador Persistente: http://hdl.handle.net/11449/198024
Origem: Oasisbr
Assunto(s): Cancer; Chemoimmunotherapy; Piecewise smooth vector fields; Typical singularities; Cancer; Cancer; Chemoimmunotherapy; Chemoimmunotherapy; Piecewise smooth vector fields; Piecewise smooth vector fields; Typical singularities; Typical singularities
Made available in DSpace on 2020-12-12T00:56:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-15
The application of sliding mode control and piecewise smooth vector fields in cancer is an incipient research area. Here we propose a piecewise dynamics to explore chemoimmunotherapeutic strategies. We investigate the dynamic behavior of the discontinuous mathematical model and we observe the occurrence of typical singularities. The on-off treatment strategies are defined in terms of a time-dependent variable such as the number of cancer or immune cells.
UNICAMP FT
UNESP IBB
USP FFCLRP, Ribeirão Preto
UNESP, IBILCE, São José do Rio Preto
UNESP IBB
UNESP, IBILCE, São José do Rio Preto
