The Use of Sentinel Lymph Node Biopsy in BRCA1/2 Mutation Carriers Undergoing Prophylactic Mastectomy: A Retrospective Consecutive Case-Series Study

• Author(s): Câmara, Sara ; Pereira, Daniela ; André, Saudade ; Mira, Beatriz ; Vaz, Fátima ; Oom, Rodrigo ; Marques, José Carlos ; Leal de Faria, João ; Rodrigues dos Santos, Catarina
• Date: 2018
• Persistent ID: http://hdl.handle.net/10400.26/32236
• Origin: Serviço de Saúde da Região Autónoma da Madeira, E.P.E.
• Subject(s): sentinel lymph node; mastectomy; BRCA mutations; occult carcinoma; morbidity; prophyltic mastectomy; Madeira Island; occult carcinoma; follow-up
• Document Type: Journal article
• Language: English
• Contributor(s): Repositório Comum

Description

Sentinel lymph node biopsy in prophylactic mastectomy is controversial. It avoids lymphadenectomy in occult carcinoma but is associated with increased morbidity. Women with BRCA mutations have a higher incidence of occult carcinoma and our objective was to assess the clinical utility of sentinel lymph node biopsy when these women undergo prophylactic mastectomy.