Author(s): Ângelo, David Faustino ; Gil, Florencio Monje ; González-García, Raúl ; Mónico, Lisete ; Sousa, Rita ; Neto, Lia ; Caldeira, Inês ; Moura, Carla ; Francisco, Luís Carlos ; Sanz, David ; Alves, Nuno ; Salvado, Francisco ; Morouço, Pedro
Date: 2018
Persistent ID: http://hdl.handle.net/10400.26/33033
Origin: Egas Moniz - Cooperativa de Ensino Superior, CRL
Subject(s): Black merino sheep; Discectomy; Discopexy; Kinematics; Preclinical trial; TMJ
Background: The temporomandibular joint interposal study (TEMPOJIMS) is a rigorous preclinical trial divided in 2 phases. In phase 1 the authors investigated the role of the TMJ disc and in phase 2 the authors evaluated 3 different interposal materials. The present work of TEMPOJIMS - phase 1, investigated the effects of bilateral discectomy and discopexy in sheep mastication and rumination. Methods: This randomized, blinded and controlled preclinical trial (in line with the ARRIVE guidelines) was conducted in 9 Black Merino sheep to evaluate changes in mastication and rumination after bilateral discectomy and bilateral discopexy, by comparing with a sham surgery control group. The outcomes evaluated were: (1) absolute masticatory time; (2) ruminant time per cycle; (3) ruminant kinematics, and (4) ruminant area. After baseline evaluation and surgical interventions, the outcomes were recorded over 3 successive days, every 30 days, for 6 months. Results: The first month after intervention seemed to be the critical period for significant kinematic changes in the discectomy and discopexy groups. However, 6 months after the bilateral interventions, no significant changes were noticed when compared with the control group. Conclusions: In this study, bilateral discectomy and discopexy had no significant effect in mastication and ruminatory movement. The introduction of kinematic evaluation presents a new challenge that may contribute to the improvement of future studies on the TMJ domain.
