Author(s): Torres,Karen Cecília de Lima ; Santos,Rodrigo Ribeiro dos ; Mapa,Filipe Camilo ; Moraes,Flávia Lanna de ; Moraes,Edgar Nunes de ; Silva,Marco Aurélio Romano
Date: 2012
Origin: Oasisbr
Subject(s): Pharmacological biomarkers, Alzheimer disease, diagnosis.
OBJECTIVE: To present the ongoing researches for biomarkers in Alzheimer disease
METHODS: Bibliographic review, starting from 2000, utilizing PubMed data bank.
RESULTS: This revision presents the actual evidences of the main markers involved in Alzheimer disease including the molecular (presented in blood and cerebrospinal fluid), the associated with image (pósitron emission tomography, single photon emission computed tomography and magnetic ressonance) and neural networks.
CONCLUSIONS: Finding an efficient biomarker will enable significative progress in the clinic evaluation and in the disease development approaches, also, will contribute to the increment of new therapeutic estrategies.
