Secretome of umbilical cord mesenchymal stem cells: Potential effects on melanoma

• Autor(es): Fernandes, Pablo ; Gomes, Andreia ; Coelho, Pedro
• Data: 2023
• Identificador Persistente: http://hdl.handle.net/10400.22/25524
• Origem: Repositório Científico do Instituto Politécnico do Porto
• Assunto(s): Melanoma; Human umbilical cord
• Tipo de Documento: Artigo científico
• Idioma: Inglês
• Contribuidor(es): REPOSITÓRIO P.PORTO

Descrição

Melanoma, a tumor resulting from the malignant transformation of melanocytes, is characterized by its aggressive nature and propensity to metastasize. Current treatment options for advanced melanoma are limited and mostly ineffective, highlighting the need for novel therapeutic approaches. Mesenchymal stem cells (MSCs) have increased considerable attention due to their anti-cancer and immunomodulatory properties. In particular, human umbilical cord MSCs (hUCMSCs) have shown promise in various therapeutic applications.