Anticancer potential of spores of the soil fungus Pisolithus tinctorius

• Author(s): Oliveira, Rui S. ; Alves, Ricardo ; Preto, Marco ; Martins, Rosário
• Date: 2018
• Persistent ID: http://hdl.handle.net/10400.22/25674
• Origin: Repositório Científico do Instituto Politécnico do Porto
• Subject(s): Pisolithus tinctorius spores; Crude extract; Fractions; Anticancer potential; Cytotoxicity
• Document Type: Conference object
• Language: English
• Contributor(s): REPOSITÓRIO P.PORTO

Description

Cancer is one of the major causes of death worldwide being the search for new anticancer drugs essential for the treatment of this disease. The sporocarps of the soil fungus Pisolithus tinctorius contain pisosterol, a triterpene that has been shown to have antitumor activity against some cancer cell lines. Nevertheless, no studies have focused on the anticancer potential of other structures such as spores, and so the anticancer potential of P. tinctorius, remains largely unknown. The main objective of this study was to evaluate the potential of P. tinctorius spores as a source of anticancer compounds.