Author(s): Raimundo Fernandes, S ; Baldaia, C ; Pinto Marques, H ; Tortosa, F ; Ramalho, F
Date: 2017
Persistent ID: http://hdl.handle.net/10400.17/2730
Origin: Repositório do Centro Hospitalar de Lisboa Central, EPE
Subject(s): CHLC CHBPT; Adenocarcinoma, Clear Cell/diagnosis; Adenocarcinoma, Clear Cell/pathology; Bile Duct Neoplasms/diagnosis; Bile Duct Neoplasms/pathology; Bile Ducts, Intrahepatic/pathology; Cholangiocarcinoma/diagnosis; Cholangiocarcinoma/pathology
Clear-cell cholangiocarcinoma is a very uncommon variant of cholangiocarcinoma with a largely unknown natural history and prognosis. We report a case of a 51-year-old previously healthy woman presenting with a large liver nodule found on routine imaging. Needle biopsy of the lesion suggested a non-hepatocellular carcinoma. After extensive workup for other primary neoplasms, the patient underwent a partial hepatectomy. Histopathology was compatible with a moderately differentiated clear-cell cholangiocarcinoma. There was no evidence of liver disease in the remaining tissue. The patient underwent chemotherapy and remains in clinical remission after two years.
