Detection of cryptic species of Aspergillus with reduced susceptibility to antifungal agents in hospitals

• Author(s): Sabino, Raquel ; Viegas, C. ; Veríssimo, C. ; Carolino, E. ; Brandão, João ; Simões, H. ; Martins, C. ; Clemons, K.V. ; Stevens, D.A.
• Date: 2015
• Persistent ID: http://hdl.handle.net/10400.18/3354
• Origin: Repositório Científico do Instituto Nacional de Saúde
• Subject(s): Aspergillus; Cryptic Species; Hospital Environment; Nosocomial Infections; Antifungal Resistence; Infeções Nosocomiais; Infecções Sistémicas e Zoonoses
• Document Type: Conference object
• Language: English
• Contributor(s): Repositório Científico do Instituto Nacional de Saúde

Description

Invasive aspergillosis is a fungal infection caused by Aspergillus spp. affecting mainly the immunocompromised. The mortality rate may reach 85%. Aspergillus identification should be based on molecular methods as there are species morphologically similar but distinct at the molecular level (cryptic species), with variable antifungal susceptibility profiles.