Detection of cryptic species of Aspergillus with reduced susceptibility to antifungal agents in hospitals

• Autor(es): Sabino, Raquel ; Viegas, C. ; Veríssimo, C. ; Carolino, E. ; Brandão, João ; Simões, H. ; Martins, C. ; Clemons, K.V. ; Stevens, D.A.
• Data: 2015
• Identificador Persistente: http://hdl.handle.net/10400.18/3354
• Origem: Repositório Científico do Instituto Nacional de Saúde
• Assunto(s): Aspergillus; Cryptic Species; Hospital Environment; Nosocomial Infections; Antifungal Resistence; Infeções Nosocomiais; Infecções Sistémicas e Zoonoses
• Tipo de Documento: Objeto de conferência
• Idioma: Inglês
• Contribuidor(es): Repositório Científico do Instituto Nacional de Saúde

Descrição

Invasive aspergillosis is a fungal infection caused by Aspergillus spp. affecting mainly the immunocompromised. The mortality rate may reach 85%. Aspergillus identification should be based on molecular methods as there are species morphologically similar but distinct at the molecular level (cryptic species), with variable antifungal susceptibility profiles.