Exosomal microRNAs as possible biomarkers for a rare disease affecting lipids

• Author(s): Encarnação, Marisa ; David, Hugo ; Ribeiro, Isaura ; Vieira, Luís ; Carneiro Silva, Catarina ; Martins, Esmeralda ; Cardoso, Maria Teresa ; Futerman, Anthony H. ; Quelhas, Dulce ; Alves, Sandra
• Date: 2023
• Persistent ID: http://hdl.handle.net/10400.18/9141
• Origin: Repositório Científico do Instituto Nacional de Saúde
• Subject(s): Rare Disease; MicroRNAs; Lysosomal Storage Disorder; Genética Humana; Doenças Genéticas
• Document Type: Conference object
• Language: English
• Contributor(s): Repositório Científico do Instituto Nacional de Saúde

Description

Exosomes mediate the communication between cells and the characterization of their content can provide important insights into health and disease. Their cargo includes proteins, lipids and nucleic acids (including microRNAs (miRNAs)). miRNAs regulate many cellular processes, including metabolism. (...)