Autor(es):
Merikanto, Ilona ; Dauvilliers, Yves ; Chung, Frances ; Wing, Yun Kwok ; de Gennaro, Luigi ; Holzinger, Brigitte ; Bjorvatn, Bjørn ; Morin, Charles M. ; Penzel, Thomas ; Benedict, Christian ; Koscec Bjelajac, Adrijana ; Chan, Ngan Yin ; Espie, Colin A. ; Hrubos-Strøm, Harald ; Inoue, Yuichi ; Korman, Maria ; Landtblom, Anne Marie ; Léger, Damien ; Matsui, Kentaro ; Mota-Rolim, Sergio ; Nadorff, Michael R. ; Plazzi, Giuseppe ; Reis, Cátia ; Yordanova, Juliana ; Partinen, Markku
Data: 2023
Identificador Persistente: http://hdl.handle.net/10400.14/39145
Origem: Veritati - Repositório Institucional da Universidade Católica Portuguesa
Assunto(s): COVID-19; Excessive daytime sleepiness; Fatigue; Insomnia; Pandemic; Post-acute sequelae of COVID-19
Descrição
Many people report suffering from post-acute sequelae of COVID-19 or “long-COVID”, but there are still open questions on what actually constitutes long-COVID and how prevalent it is. The current definition of post-acute sequelae of COVID-19 is based on voting using the Delphi-method by the WHO post-COVID-19 working group. It emphasizes long-lasting fatigue, shortness of breath and cognitive dysfunction as the core symptoms of post-acute sequelae of COVID-19. In this international survey study consisting of 13,628 subjects aged 18–99 years from 16 countries of Asia, Europe, North America and South America (May–Dec 2021), we show that post-acute sequelae of COVID-19 symptoms were more prevalent amongst the more severe COVID-19 cases, i.e. those requiring hospitalisation for COVID-19. We also found that long-lasting sleep symptoms are at the core of post-acute sequelae of COVID-19 and associate with the COVID-19 severity when COVID-19 cases are compared with COVID-negative cases. Specifically, fatigue (61.3%), insomnia symptoms (49.6%) and excessive daytime sleepiness (35.8%) were highly prevalent amongst respondents reporting long-lasting symptoms after hospitalisation for COVID-19. Understanding the importance of sleep-related symptoms in post-acute sequelae of COVID-19 has a clinical relevance when diagnosing and treating long-COVID.
