Very late-onset amyotrophic lateral sclerosis in a Portuguese cohort

• Author(s): Oliveira Santos, Miguel ; Gromicho, Marta ; Pinto, Susana ; Carvalho, Mamede
• Date: 2018
• Persistent ID: http://hdl.handle.net/10451/54330
• Origin: Repositório da Universidade de Lisboa
• Subject(s): Amyotrophic lateral sclerosis; Late-onset; Old; Prognosis; Survival
• Document Type: Journal article
• Language: English
• Contributor(s): Repositório Científico de Acesso Aberto da ULisboa

Description

Objective: Although amyotrophic lateral sclerosis (ALS) incidence has been stable among Western countries, population-ageing effect will probably increase the proportion of very-old ALS patients. We aim to study this population. Methods: A retrospective study was performed, including 1083 ALS patients followed longitudinally in our ALS unit from January 1995 to December 2017. The patients were divided in two groups, according to age at disease onset (