Absence of microsatellite instability in soft tissue sarcomas

• Author(s): Campanella, Nathália C. ; Penna, Valter ; Ribeiro, Guilherme ; Abrahão-Machado, Lucas Faria ; Scapulatempo-Neto, Cristovam ; Reis, R. M.
• Date: 2015
• Persistent ID: https://hdl.handle.net/1822/62217
• Origin: RepositóriUM - Universidade do Minho
• Subject(s): Soft tissue sarcomas; Microsatellite instability; DNA repair proteins
• Document Type: Journal article
• Language: English
• Contributor(s): Universidade do Minho

Description

Here, we analyze a series of soft tissue sarcomas (STS), which are a heterogeneous group of mesenchymal neoplasms, for the presence and frequency of microsatellite instability (MSI). MSI has been proposed to be clinically relevant for colorectal cancer, yet on STS its role is not consensual, partly due to the limited number of cases analyzed and methodology issues.