Author(s): Pereira, Anabela ; Cardoso, Vanessa Fernandes ; Martins, Marcos Silva ; Fernandes, Nuno Alexandre Tavares Campos ; Carvalho, Óscar Samuel Novais
Date: 2025
Persistent ID: https://hdl.handle.net/1822/96140
Origin: RepositóriUM - Universidade do Minho
Subject(s): Needle Hydrophone; Biomedical Ultrasound; Neurodegenerative Diseases; Phantom
In the past years, the prevalence of neurodegenerative diseases has in-creased, highlighting the urgent need to better understand and combat these diseases. Innovative ultrasound treatments have shown promising results but require further investigation, particularly regarding the pene-tration of acoustic waves into the brain. This work focus on developing a hydrophone to study acoustic wave penetration in biological tissue, com-bining computational simulations and experimental testing. The hydro-phone design was optimized for accurate measurements of wave interac-tions with tissue, and experiments using gelatine and biological tissue samples validated its performance. The results show the hydrophone’s potential to measure acoustic wave interactions in heterogeneous tissues, providing a foundation for optimizing therapeutic ultrasound in neuro-degenerative diseases. Further refinements are needed to improve accu-racy in more complex conditions.
