Cryptococcal meningitis in pregnancy: review of the literature. Report of two cases

• Author(s): Pereira, Carlos Alberto Pires ; Fischman, Olga ; Colombo, Arnaldo Lopes ; Moron, Antonio Fernandes ; Pignatari, Antonio Carlos Campos
• Date: 1993
• Origin: Oasisbr
• Subject(s): Neurocriptococose; Gravidez; Anfotericina B; Flucitosina
• Document Type: Journal article
• Language: Portuguese

Description

Two cases of neurocryptococcosis were diagnosed during pregnancy in São Paulo (Brazil). Amphotericin B was used in the second trimester in one patient. The other, received amphotericin B during the first trimester of pregnancy and 5-fluorocytosine was added in the second trimester. In both, the pregnancy was uneventful and the fetus suffered no damage. The therapy used to treat pregnant women with cryptococcal meningitis is commented. The newborn follow-up is discussed. A review of the literature concerning neurocryptococcosis during pregnancy is presented.

São descritos os dois primeiros casos de neurocriptococose durante a gravidez diagnosticados em São Paulo (Brasil). Uma paciente foi tratada com anfotericina B no segundo trimestre, a outra, com anfotericina B no primeiro trimestre e no 2º trimestre com anfotericina B e 5 flucitosina. Ambas tiveram boa evolução materna e fetal. É apresentada revisão da literatura da neurocriptococose em gestantes.