Author(s): Lemos, J ; Pereira, D ; Amorim, M ; Santiago, B ; Paiva, A ; Cunha, L
Date: 2014
Persistent ID: http://hdl.handle.net/10400.4/2155
Origin: Repositório do Centro Hospitalar e Universitário de Coimbra
Subject(s): Movimentos Oculares; Nistagmo Patológico; Área Tegmentar Ventral
We describe a patient with downbeat nystagmus (DBN) evoked only by eye closure. Brain and spinal cord magnetic resonance imaging revealed a T2 paramedian lesion in the left lower basis pontis and other white matter lesions consistent with multiple sclerosis. One potential mechanism for DBN in this case involves transverse ephaptic spread of excitation from areas that subserve coordinated lid closure to the decussating ventral tegmental tract.
