Author(s): Oliveira,Raquel ; Gonçalo,Margarida ; Faria,Carlos ; Donaire,David ; Barbosa,Benilde ; Cardoso,José Carlos ; Julião,Maria José ; Moura,José ; Carvalho,Armando
Date: 2020
Origin: SciELO Portugal
Subject(s): Coronavirus Infections; COVID-19; Exanthema; SARS-CoV-2.
ABSTRACT We report a case of a 84-year-old male hospitalized for bacterial pneumonia who, during hospitalization, developed a flexural exanthema in parallel with a positive swab for SARS-CoV-2. Supportive therapy was instituted, the rash disappeared in 7 days and the patient fully recovered. At the same time, two other cases of SARS-CoV-2 infection occurred in the same ward. Histopathology and immunohistochemistry of a skin biopsy showed a scarce predominantly perivascular lymphocytic infiltration in the upper dermis, predominantly by CD4+ T cells, a slight epidermotropism, spongiosis and focal parakeratosis, compatible with a viral exanthema or a maculopapular drug eruption. Patch testing with possible culprit drugs were negative. We seek to add value in understanding all the manifestations of SARS-CoV-2 infection and to draw attention to the importance of early identification of skin manifestations in association with COVID-19.
