Author(s): Martins, Pedro Manuel Abreu ; Ribeiro, S. ; Ribeiro, C. ; Sencadas, V. ; Gomes, Andreia C ; Gama, F. M. ; Lanceros-Méndez, S.
Date: 2013
Persistent ID: https://hdl.handle.net/1822/27040
Origin: RepositóriUM - Universidade do Minho
Subject(s): Science & Technology
This work reports on the influence of polarization and morphology of electroactive poly(vinylidene fluoride), PVDF, on the adhesion and morphology of myoblast cells. Non-poled, ‘‘poled +’’ and “poled-“ β-PVDF films were prepared by solvent casting followed by corona poling. Further, random and aligned electrospun β-PVDF fiber mats were also prepared. It is demonstrated that negatively charged surfaces improve cell adhesion and proliferation and that the directional growth of the myoblast cells can be achieved by culturing the cell on aligned fibers. Therefore, the potential application of electroative materials for muscle regeneration is demonstrated.
