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Heterogeneous contributions of change in population distribution of body mass i...

Iurilli, Maria L. C.; Zhou, Bin; Bennett, James E.; Carrillo-Larco, Rodrigo M.; Sophiea, Marisa K.; Rodriguez-Martinez, Andrea; Bixby, Honor

Made available in DSpace on 2022-04-28T19:30:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-01; From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in the prevalence of ...

Data: 2022   |   Origem: Oasisbr

Worldwide trends in hypertension prevalence and progress in treatment and contr...

Zhou, Bin; Carrillo-Larco, Rodrigo M.; Danaei, Goodarz; Riley, Leanne M.; Paciorek, Christopher J.; Stevens, Gretchen A.; Gregg, Edward W.

Made available in DSpace on 2022-04-28T17:23:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-09-11; WHO; Abdul Latif Jameel Institute for Disease and Emergency Analytics - Community Jameel, at Imperial College London, London, UK; British Heart Foundation (Centre of Research Excellence); Background Hypertension can be detected at the primary health-care level and low-cost treatments can effectively con...

Data: 2022   |   Origem: Oasisbr

The potential of current polygenic risk scores to predict high myopia and myopi...

Kassam, Irfahan; Foo, Li-Lian; Lança, Carla; Xu, Ling Qian; Hoang, Quan V.; Cheng, Ching-Yu; Hysi, Pirro; Saw, Seang-Mei

Purpose: To evaluate the trans-ancestry portability of current myopia polygenic risk scores (PRS) to predict high myopia (HM) and myopic macular degeneration (MMD) in an Asian population. Design: Population-based study. Subjects: A total of 5,894 (2,141 Chinese, 1,913 Indians, and 1,840 Malays) adults from the Singapore Epidemiology of Eye Diseases (SEED) study were included in the analysis. The mean age was 57...


Heterogeneous contributions of change in population distribution of body mass i...

Iurilli, Maria L. C.; Zhou, Bin; Bennett, James E.; Carrillo-Larco, Rodrigo M.; Sophiea, Marisa K.; Rodriguez-Martinez, Andrea; Bixby, Honor

Made available in DSpace on 2021-06-25T15:08:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-09; Wellcome Trust; From 1985 to 2016, the prevalence of underweight decreased, and that of obesity and severe obesity increased, in most regions, with significant variation in the magnitude of these changes across regions. We investigated how much change in mean body mass index (BMI) explains changes in th...

Data: 2021   |   Origem: Oasisbr

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a populati...

Chauhan, Ganesh; Adams, Hieab H.H.; Satizabal, Claudia L.; Bis, Joshua C.; Teumer, Alexander; Sargurupremraj, Muralidharan; Hofer, Edith

Objective: To explore genetic and lifestyle risk factors of MRI-defined brain infarcts (BI) in large population-based cohorts. Methods: We performed meta-analyses of genome-wide association studies (GWAS) and examined associations of vascular risk factors and their genetic risk scores (GRS) with MRI-defined BI and a subset of BI, namely, small subcortical BI (SSBI), in 18 population-based cohorts (n = 20,949) f...


Worldwide trends in body-mass index, underweight, overweight, and obesity from ...

Ezzati, Majid; Bentham, James; Di Cesare, Mariachiara; Bilano, Ver; Bixby, Honor; Zhou, Bin; Stevens, Gretchen A.; Riley, Leanne M.; Taddei, Cristina

Made available in DSpace on 2018-11-26T20:04:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-12-16; Wellcome Trust; AstraZeneca; Background Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cove...

Data: 2018   |   Origem: Oasisbr

Contributions of mean and shape of blood pressure distribution to worldwide tre...

Zhou, Bin; Bentham, James; Di Cesare, Mariachiara; Bixby, Honor; Danaei, Goodarz; Hajifathalian, Kaveh; Taddei, Cristina; Carrillo-Larco, Rodrigo M.

Made available in DSpace on 2018-11-26T22:38:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-06-01; Wellcome Trust; Background: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successfu...

Data: 2018   |   Origem: Oasisbr

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479...

Zhou, Bin; Bentham, James; Di Cesare, Mariachiara; Bixby, Honor; Danaei, Goodarz; Cowan, Melanie J; Paciorek, Christopher J; Singh, Gitanjali

Background Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher. Methods For this analysis, we poo...


Worldwide trends in body-mass index, underweight, overweight, and obesity from ...

Abarca-Gómez, Leandra; Abdeen, Ziad A~.; Hamid, Zargar Abdul; Abu-Rmeileh, Niveen M.; Acosta-Cazares, Benjamin; Acuin, Cecilia; Adams, Robert J.

Background Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. Methods We pooled 2416 population-based s...


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