Author(s): Alves, Celso ; Pinteus, Susete ; Simões, Tiago ; Horta, André ; Silva, Joana ; Tecelão, Carla ; Pedrosa, Rui
Date: 2016
Persistent ID: http://hdl.handle.net/10400.8/13205
Origin: IC-online
Subject(s): Antimicrobial agents; antioxidant activity; Bioassays; Ffatty acids; Natural products; Nutrition; Seaweeds
The aim of this work was to study the proximate composition and the bioactive profile of Bifurcariabifurcata. It contains 73.31 0.69% of moisture, 8.57 0.11 g per 100 g dry weight (d.w.) of protein,5.81 0.14 g per 100 g d.w. of lipid content and 30.15 0.00 g per 100 g d.w. of ash. The polyunsatu-rated fatty acids were the most abundant fatty acid (FA), accounting for 2426.56 mg per 100 g which rep-resents 41.77% of the total FA. The methanolic fraction showed high quantity of polyphenols (220.01 0.010 phloroglucinol equivalents g 1 extract), DPPH radical reduction capacity (EC 50:58.82 lg mL 1)and oxygen radical absorbent capacity (3151.35 119.33 lmol Trolox equivalents g 1 extract). Thehighest antimicrobial effect was observed against Pseudomonas aeruginosa (11.3 1.5 mm) and Sac-charomyces cerevisiae (IC 50 :17.07 lg mL 1 ) induced by methanolic and dichloromethane fractions,respectively. Dichloromethane fraction revealed the highest antitumor activity on Caco-2 and HepG-2 cells. Bifurcaria bifurcata can be a promising source of bioactive compounds and functionalingredients.
