Document details

An insight on the role of photosensitizer nanocarriers for Photodynamic Therapy

Author(s): Mesquita, Mariana Q. ; Dias, Cristina J. ; Gamelas, Sara ; Fardilha, Margarida ; Neves, Maria G. P. M. S. ; Faustino, Maria Amparo F.

Date: 2018

Persistent ID: http://hdl.handle.net/10773/29214

Origin: RIA - Repositório Institucional da Universidade de Aveiro

Subject(s): Photodynamic therapy; Drug delivery; Liposomes; Silica nanoparticles; Gold nanoparticles; Polymeric micelles


Description

Photodynamic therapy (PDT) is a modality of cancer treatment in which tumor cells are destroyed by reactive oxygen species (ROS) produced by photosensitizers following its activation with visible or near infrared light. The PDT success is dependent on different factors namely on the efficiency of the photosensitizer deliver and targeting ability. In this review a special attention will be given to the role of some drug delivery systems to improve the efficiency of tetrapyrrolic photosensitizers to this type of treatment.

Document Type Journal article
Language English
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