Publicação
Oncology Referral Concerning Paediatric Neurosurgery? Analysis of the Situation between 2008-2013 in the North of Portugal
| Resumo: | Introduction: Primary central nervous system tumours represent the second most frequent neoplasm and are the leading cause of death from solid tumours in children. Our study aimed to provide the most up-to-date epidemiological analysis of primary central nervous system tumours in children living in the north of Portugal and to explore a possible effect of the centralisation of care on outcomes.Material and Methods: This population-based study included all newly diagnosed and histologically confirmed primary central nervous system tumours in people below 18 years old, living in the north of Portugal, from January 2008 to December 2013. Data were collected through access to clinical files. We described children and tumour characteristics, and analysed patient: paediatric neurosurgeon and histological tumour type: paediatric neurosurgeon ratios.Results: A total of 147 cases was recorded. Mean age at diagnosis of primary central nervous system tumours was 8.0 ± 5.2 years. Astrocytomas were the most common histological type (34%). We found that World Health Organization Tumour Grade was the only variable of statistically significant influence in mortality (p = 0.001). 1-, 3- and 5-year survivals related to 2008-2013 period were statistically higher than 2005 - 2007. Astrocytomas have the highest survival rate, with statistically significant difference from other tumours (p = 0.015). We estimated a mean of 12.25 treated cases per year by each paediatric neurosurgeon at our institution.Discussion: Our results are globally consistent with those published all over the world, but we reported the highest survival rates. The number of cases treated per year by each neurosurgeon is accordant to the recommended.Conclusion: We showed an improvement when comparing to data previous to 2008 and better results than those from previous studies, namely higher survival at 1-, 3- and 5-years from the diagnosis, with low complication and relapsing rates. Therefore, the referral of primary central nervous system tumours cases to centres with larger experience can be invaluable for the achievement of the best outcomes. |
|---|---|
| Autores principais: | Batista, Ana |
| Outros Autores: | Nogueira-Silva, Luís; Vaz, Rui; Oliveira, Joana |
| Assunto: | Central Nervous System Neoplasms/epidemiology Central Nervous System Neoplasms/surgery Child Neurosurgery Portugal Referral and Consultation. Criança Neoplasias do Sistema Nervoso Central/cirurgia Neoplasias do Sistema Nervoso Central/epidemiologia Neurocirurgia Portugal Referência e Consulta. |
| Ano: | 2016 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | unknown |
| Instituição associada: | Ordem dos Médicos |
| Idioma: | inglês |
| Origem: | Acta Médica Portuguesa |
| _version_ | 1867503005316677632 |
|---|---|
| author | Batista, Ana |
| author2 | Nogueira-Silva, Luís Vaz, Rui Oliveira, Joana |
| author2_role | author author author |
| author_facet | Batista, Ana Nogueira-Silva, Luís Vaz, Rui Oliveira, Joana |
| author_role | author |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Batista, Ana\"},{\"Person.name\":\"Nogueira-Silva, Luís\"},{\"Person.name\":\"Vaz, Rui\"},{\"Person.name\":\"Oliveira, Joana\"}] |
| datacite.creators.creator.creatorName.fl_str_mv | Batista, Ana Nogueira-Silva, Luís Vaz, Rui Oliveira, Joana |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Central Nervous System Neoplasms/epidemiology Central Nervous System Neoplasms/surgery Child Neurosurgery Portugal Referral and Consultation. Criança Neoplasias do Sistema Nervoso Central/cirurgia Neoplasias do Sistema Nervoso Central/epidemiologia Neurocirurgia Portugal Referência e Consulta. |
| datacite.titles.title.fl_str_mv | Oncology Referral Concerning Paediatric Neurosurgery? Analysis of the Situation between 2008-2013 in the North of Portugal Referenciação Oncológica em Neurocirurgia Pediátrica? Análise da Situação no Norte de Portugal entre 2008-2013 |
| dc.creator.none.fl_str_mv | Batista, Ana Nogueira-Silva, Luís Vaz, Rui Oliveira, Joana |
| dc.description.none.fl_str_mv | Introdução: Os tumores primários do sistema nervoso central representam o segundo grupo de neoplasias mais frequente e são a principal causa de morte devido a tumores sólidos em crianças. O nosso estudo teve como objetivos realizar a mais atualizada análise epidemiológica desta doença no norte de Portugal e avaliar o possível benefício da centralização de cuidados.Material e Métodos: Este estudo de base populacional incluiu todos os tumores primários do sistema nervoso central diagnosticados e histologicamente confirmados em indivíduos menores de 18 anos de idade, que residem no norte do país, desde Janeiro 2008 até Dezembro 2013. Os dados foram obtidos por meio da avaliação dos processos clínicos dos doentes. Nós descrevemos as características das crianças e dos seus tumores e analisámos os quocientes doente: neurocirurgião pediátrico e tipo histológico de tumor: neurocirurgião pediátrico e as taxas de sobrevivência, mortalidade, complicações e recidiva.Resultados: Foram registados 147 casos. A média de idade ao diagnóstico foi de 8,0 ± 5,2 anos. Os astrocitomas foram o tipo histológico mais frequentemente encontrado (34%). O tipo histológico foi a única variável com influência estatisticamente significativa na mortalidade (p = 0,001). As sobrevivências a um, três e cinco anos relativas ao período entre 2008 - 2013 foram estatisticamente superiores às do intervalo entre 2005 - 2007. Os astrocitomas apresentam a mais alta taxa de sobrevivência, sendo estatisticamente diferente dos outros tipos de tumor (p = 0,015). Estimámos uma média de 12,25 casos tratados anualmente por neurocirurgião pediátrico no nosso hospital.Discussão: Os nossos resultados são, globalmente, consistentes com os encontrados na literatura mundial, mas registrámos taxas de sobrevivência mais altas. O número de casos tratados por neurocirurgião pediátrico está de acordo com o recomendado.Conclusão: Demonstrámos que houve melhoria dos outcomes em estudo em relação aos obtidos previamente a 2008 e aos reportados por outros estudos, nomeadamente taxas de sobrevivência a um, três e cinco anos após o diagnóstico mais elevadas, com índices de complicações e recidiva baixos. Neste sentido, a referenciação destes casos para centros de vasta experiência pode ser de valor inestimável para se obter os melhores resultados. |
| dc.format.none.fl_str_mv | application/pdf application/msword application/pdf |
| dc.identifier.none.fl_str_mv | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6432 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Ordem dos Médicos |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.source.none.fl_str_mv | Acta Médica Portuguesa; Vol. 29 No. 1 (2016): January; 15-23 Acta Médica Portuguesa; Vol. 29 N.º 1 (2016): Janeiro; 15-23 1646-0758 0870-399X |
| dc.subject.none.fl_str_mv | Central Nervous System Neoplasms/epidemiology Central Nervous System Neoplasms/surgery Child Neurosurgery Portugal Referral and Consultation. Criança Neoplasias do Sistema Nervoso Central/cirurgia Neoplasias do Sistema Nervoso Central/epidemiologia Neurocirurgia Portugal Referência e Consulta. |
| dc.title.fl_str_mv | Oncology Referral Concerning Paediatric Neurosurgery? Analysis of the Situation between 2008-2013 in the North of Portugal Referenciação Oncológica em Neurocirurgia Pediátrica? Análise da Situação no Norte de Portugal entre 2008-2013 |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Introduction: Primary central nervous system tumours represent the second most frequent neoplasm and are the leading cause of death from solid tumours in children. Our study aimed to provide the most up-to-date epidemiological analysis of primary central nervous system tumours in children living in the north of Portugal and to explore a possible effect of the centralisation of care on outcomes.Material and Methods: This population-based study included all newly diagnosed and histologically confirmed primary central nervous system tumours in people below 18 years old, living in the north of Portugal, from January 2008 to December 2013. Data were collected through access to clinical files. We described children and tumour characteristics, and analysed patient: paediatric neurosurgeon and histological tumour type: paediatric neurosurgeon ratios.Results: A total of 147 cases was recorded. Mean age at diagnosis of primary central nervous system tumours was 8.0 ± 5.2 years. Astrocytomas were the most common histological type (34%). We found that World Health Organization Tumour Grade was the only variable of statistically significant influence in mortality (p = 0.001). 1-, 3- and 5-year survivals related to 2008-2013 period were statistically higher than 2005 - 2007. Astrocytomas have the highest survival rate, with statistically significant difference from other tumours (p = 0.015). We estimated a mean of 12.25 treated cases per year by each paediatric neurosurgeon at our institution.Discussion: Our results are globally consistent with those published all over the world, but we reported the highest survival rates. The number of cases treated per year by each neurosurgeon is accordant to the recommended.Conclusion: We showed an improvement when comparing to data previous to 2008 and better results than those from previous studies, namely higher survival at 1-, 3- and 5-years from the diagnosis, with low complication and relapsing rates. Therefore, the referral of primary central nervous system tumours cases to centres with larger experience can be invaluable for the achievement of the best outcomes. |
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| eu_rights_str_mv | unknown |
| format | article |
| id | amp_17dfd0b5b590a2bf46e60fa6d81283cd |
| identifier.url.fl_str_mv | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6432 |
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| institution | Ordem dos Médicos |
| instname_str | Ordem dos Médicos |
| language | eng |
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| network_name_str | Acta Médica Portuguesa |
| oai_identifier_str | oai:ojs.www.actamedicaportuguesa.com:article/6432 |
| organization_str_mv | urn:organizationAcronym:om |
| person_str_mv | Batista, Ana Nogueira-Silva, Luís Vaz, Rui Oliveira, Joana |
| publishDate | 2016 |
| publisher.none.fl_str_mv | Ordem dos Médicos |
| reponame_str | Acta Médica Portuguesa |
| repository_id_str | urn:repositoryAcronym:amp |
| service_str_mv | urn:repositoryAcronym:amp |
| spelling | en-USOncology Referral Concerning Paediatric Neurosurgery? Analysis of the Situation between 2008-2013 in the North of Portugalpt-PTReferenciação Oncológica em Neurocirurgia Pediátrica? Análise da Situação no Norte de Portugal entre 2008-2013Batista, AnaNogueira-Silva, LuísVaz, RuiOliveira, JoanaCentral Nervous System Neoplasms/epidemiologyCentral Nervous System Neoplasms/surgeryChildNeurosurgeryPortugalReferral and Consultation.CriançaNeoplasias do Sistema Nervoso Central/cirurgiaNeoplasias do Sistema Nervoso Central/epidemiologiaNeurocirurgiaPortugalReferência e Consulta.Direitos de Autor (c) 2016 Copyright © Ordem dos Médicos 2016http://purl.org/coar/access_right/c_abf2https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6432URLhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6432URLHasVersionhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6432/4533URLHasVersionhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6432/7752URLHasVersionhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6432/7912URLHasVersion2016-01-29en-USIntroduction: Primary central nervous system tumours represent the second most frequent neoplasm and are the leading cause of death from solid tumours in children. Our study aimed to provide the most up-to-date epidemiological analysis of primary central nervous system tumours in children living in the north of Portugal and to explore a possible effect of the centralisation of care on outcomes.Material and Methods: This population-based study included all newly diagnosed and histologically confirmed primary central nervous system tumours in people below 18 years old, living in the north of Portugal, from January 2008 to December 2013. Data were collected through access to clinical files. We described children and tumour characteristics, and analysed patient: paediatric neurosurgeon and histological tumour type: paediatric neurosurgeon ratios.Results: A total of 147 cases was recorded. Mean age at diagnosis of primary central nervous system tumours was 8.0 ± 5.2 years. Astrocytomas were the most common histological type (34%). We found that World Health Organization Tumour Grade was the only variable of statistically significant influence in mortality (p = 0.001). 1-, 3- and 5-year survivals related to 2008-2013 period were statistically higher than 2005 - 2007. Astrocytomas have the highest survival rate, with statistically significant difference from other tumours (p = 0.015). We estimated a mean of 12.25 treated cases per year by each paediatric neurosurgeon at our institution.Discussion: Our results are globally consistent with those published all over the world, but we reported the highest survival rates. The number of cases treated per year by each neurosurgeon is accordant to the recommended.Conclusion: We showed an improvement when comparing to data previous to 2008 and better results than those from previous studies, namely higher survival at 1-, 3- and 5-years from the diagnosis, with low complication and relapsing rates. Therefore, the referral of primary central nervous system tumours cases to centres with larger experience can be invaluable for the achievement of the best outcomes.pt-PTIntrodução: Os tumores primários do sistema nervoso central representam o segundo grupo de neoplasias mais frequente e são a principal causa de morte devido a tumores sólidos em crianças. O nosso estudo teve como objetivos realizar a mais atualizada análise epidemiológica desta doença no norte de Portugal e avaliar o possível benefício da centralização de cuidados.Material e Métodos: Este estudo de base populacional incluiu todos os tumores primários do sistema nervoso central diagnosticados e histologicamente confirmados em indivíduos menores de 18 anos de idade, que residem no norte do país, desde Janeiro 2008 até Dezembro 2013. Os dados foram obtidos por meio da avaliação dos processos clínicos dos doentes. Nós descrevemos as características das crianças e dos seus tumores e analisámos os quocientes doente: neurocirurgião pediátrico e tipo histológico de tumor: neurocirurgião pediátrico e as taxas de sobrevivência, mortalidade, complicações e recidiva.Resultados: Foram registados 147 casos. A média de idade ao diagnóstico foi de 8,0 ± 5,2 anos. Os astrocitomas foram o tipo histológico mais frequentemente encontrado (34%). O tipo histológico foi a única variável com influência estatisticamente significativa na mortalidade (p = 0,001). As sobrevivências a um, três e cinco anos relativas ao período entre 2008 - 2013 foram estatisticamente superiores às do intervalo entre 2005 - 2007. Os astrocitomas apresentam a mais alta taxa de sobrevivência, sendo estatisticamente diferente dos outros tipos de tumor (p = 0,015). Estimámos uma média de 12,25 casos tratados anualmente por neurocirurgião pediátrico no nosso hospital.Discussão: Os nossos resultados são, globalmente, consistentes com os encontrados na literatura mundial, mas registrámos taxas de sobrevivência mais altas. O número de casos tratados por neurocirurgião pediátrico está de acordo com o recomendado.Conclusão: Demonstrámos que houve melhoria dos outcomes em estudo em relação aos obtidos previamente a 2008 e aos reportados por outros estudos, nomeadamente taxas de sobrevivência a um, três e cinco anos após o diagnóstico mais elevadas, com índices de complicações e recidiva baixos. Neste sentido, a referenciação destes casos para centros de vasta experiência pode ser de valor inestimável para se obter os melhores resultados.Ordem dos Médicosapplication/pdfapplication/mswordapplication/pdfen-USActa Médica Portuguesa; Vol. 29 No. 1 (2016): January; 15-23pt-PTActa Médica Portuguesa; Vol. 29 N.º 1 (2016): Janeiro; 15-231646-07580870-399Xengjournal articlehttp://purl.org/coar/resource_type/c_6501literatureVoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85 |
| spellingShingle | Oncology Referral Concerning Paediatric Neurosurgery? Analysis of the Situation between 2008-2013 in the North of Portugal Batista, Ana Central Nervous System Neoplasms/epidemiology Central Nervous System Neoplasms/surgery Child Neurosurgery Portugal Referral and Consultation. Criança Neoplasias do Sistema Nervoso Central/cirurgia Neoplasias do Sistema Nervoso Central/epidemiologia Neurocirurgia Portugal Referência e Consulta. |
| status | SINGLETON |
| status_str | VoR |
| subject.fl_str_mv | Central Nervous System Neoplasms/epidemiology Central Nervous System Neoplasms/surgery Child Neurosurgery Portugal Referral and Consultation. Criança Neoplasias do Sistema Nervoso Central/cirurgia Neoplasias do Sistema Nervoso Central/epidemiologia Neurocirurgia Portugal Referência e Consulta. |
| title | Oncology Referral Concerning Paediatric Neurosurgery? Analysis of the Situation between 2008-2013 in the North of Portugal |
| title_full | Oncology Referral Concerning Paediatric Neurosurgery? Analysis of the Situation between 2008-2013 in the North of Portugal |
| title_fullStr | Oncology Referral Concerning Paediatric Neurosurgery? Analysis of the Situation between 2008-2013 in the North of Portugal |
| title_full_unstemmed | Oncology Referral Concerning Paediatric Neurosurgery? Analysis of the Situation between 2008-2013 in the North of Portugal |
| title_short | Oncology Referral Concerning Paediatric Neurosurgery? Analysis of the Situation between 2008-2013 in the North of Portugal |
| title_sort | Oncology Referral Concerning Paediatric Neurosurgery? Analysis of the Situation between 2008-2013 in the North of Portugal |
| topic | Central Nervous System Neoplasms/epidemiology Central Nervous System Neoplasms/surgery Child Neurosurgery Portugal Referral and Consultation. Criança Neoplasias do Sistema Nervoso Central/cirurgia Neoplasias do Sistema Nervoso Central/epidemiologia Neurocirurgia Portugal Referência e Consulta. |
| topic_facet | Central Nervous System Neoplasms/epidemiology Central Nervous System Neoplasms/surgery Child Neurosurgery Portugal Referral and Consultation. Criança Neoplasias do Sistema Nervoso Central/cirurgia Neoplasias do Sistema Nervoso Central/epidemiologia Neurocirurgia Portugal Referência e Consulta. |
| url | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6432 |
| visible | 1 |