Detalhes bibliográficos
| Resumo: | Introduction: The aim of this study was to estimate and describe the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) specific antibodies (immunoglobulin M and/or immunoglobulin G) in Portugal in May-July 2020.Material and Methods: A cross-sectional seroepidemiological survey was developed after the peak of the first epidemic wave on a sample of 2301 Portuguese residents, aged 1 year or older. Survey sample was selected using a two-stage stratified non-probability sampling design (quota sampling). SARS-CoV-2 immunoglobulin M and immunoglobulin G antibodies were measured in serum samples by enzyme-linked immunosorbent assay. Seroprevalence estimates of immunoglobulin M and/or immunoglobulin G and 95% confidence intervals were stratified by sex, age group, health region and education.Results: Overall, seroprevalence was 2.9% (95% confidence interval: 2.0% - 4.2%). Higher prevalence rates were observed in male (4.1%, 95% confidence interval: 2.6% - 6.6%) and those with secondary education (6.4%, 95% confidence interval: 3.2% - 12.5%). Differences in seroprevalence by age group and region were not statistically significant.Discussion: The estimated seroprevalence of SARS-CoV-2 was higher than the cumulative incidence reported by the National Surveillance System but far from necessary to reach herd immunity.Conclusion: Our results support limited extent of infection by SARS-CoV-2 in the study population possibly due to early lockdown measures implemented in Portugal and support the need to continue monitoring of SARS-CoV-2 seroprevalence in order to increase our knowledge about the evolution of the epidemic and to estimate the proportion of the susceptible population over time. |
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| Autores principais: | Kislaya, Irina |
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| Outros Autores: | Gonçalves, Paulo; Barreto, Marta; de Sousa, Rita; Garcia, Ana Cristina; Matos, Rita; Guiomar, Raquel; Rodrigues, Ana Paula; ISNCOVID-19 Group, On behalf of |
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| Assunto: | Antibodies Viral COVID-19 COVID-19 Testing Immunoglobulin G Immunoglobulin M Portugal SARS-CoV-2 Seroepidemiologic Studies Anticorpos Antivirais COVID-19 Estudos Seroepidemiológicos Imunoglobulina G Imunoglobulina M Portugal SARS-Cov-2 Testagem COVID-19 |
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| Ano: | 2021 |
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| País: | Portugal |
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| Tipo de documento: | artigo |
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| Tipo de acesso: | unknown |
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| Instituição associada: | Ordem dos Médicos |
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| Idioma: | inglês |
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| Origem: | Acta Médica Portuguesa |
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