Publicação

Polysaccharide of Escherichia coli in the Prevention of Recurrent Urinary Tract Infection: An Evidence-Based Review

Ver documento

Detalhes bibliográficos
Resumo:Introduction: Recurrent urinary tract infection is frequent and it is related to morbidity, costs and growing antibiotic resistance. OM 8930 vaccine is composed by Escherichia coli polysaccharide and it is a possible prophylactic measure, but there is doubt as to its effectiveness.Material and Methods: We performed a systematic review in evidence-based medicine databases with rigorous bibliography selection.Results: We found an effective decrease of recurrences in test groups.Discussion: We recommend the administration of the vaccine as prophylaxis of recurrent cystitis.Conclusion: The vaccine has impact on the recurrent cystitis relapse rate. We suggest that more studies be carried out to evaluate the vaccine cost-benefit and its effectiveness in complicated urinary infections.
Autores principais:Tinoco, Manuel
Outros Autores:Santos, Mélody; Reitor, Conceição; Rodrigues, Andreia; Monteiro, João
Assunto:Adjuvants Immunologic/therapeutic use Escherichia coli Infections Urinary Tract Infections Uropathogenic Escherichia coli Adjuvantes Imunológicos/uso terapêutico Escherichia coli Uropatogénica Infecções por Escherichia coli Infecções Urinárias
Ano:2018
País:Portugal
Tipo de documento:artigo
Tipo de acesso:unknown
Instituição associada:Ordem dos Médicos
Idioma:português
Origem:Acta Médica Portuguesa

Registos relacionados

Registos relacionados