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Cortical gyrification morphology in individuals with ASD and ADHD across the lifespan: a systematic review and meta-analysis

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Resumo:Autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD) are common neurodevelopmental disorders (NDDs) that may impact brain maturation. A number of studies have examined cortical gyrification morphology in both NDDs. Here we review and when possible pool their results to better understand the shared and potentially disorder-specific gyrification features. We searched MEDLINE, PsycINFO, and EMBASE databases, and 24 and 10 studies met the criteria to be included in the systematic review and meta-analysis portions, respectively. Meta-analysis of local Gyrification Index (lGI) findings across ASD studies was conducted with SDM software adapted for surface-based morphometry studies. Meta-regressions were used to explore effects of age, sex, and sample size on gyrification differences. There were no significant differences in gyrification across groups. Qualitative synthesis of remaining ASD studies highlighted heterogeneity in findings. Large-scale ADHD studies reported no differences in gyrification between cases and controls suggesting that, similar to ASD, there is currently no evidence of differences in gyrification morphology compared with controls. Larger, longitudinal studies are needed to further clarify the effects of age, sex, and IQ on cortical gyrification in these NDDs.
Autores principais:Gharehgazlou, Avideh
Outros Autores:Freitas, Carina; Ameis, Stephanie H; Taylor, Margot J.; Lerch, Jason P.; Radua, Joaquim; Anagnostou, Evdokia
Assunto:Attention-deficit hyperactivity disorder Autism spectrum disorder Cortical gyrification lGI Structural MRI . Faculdade de Ciências da Vida
Ano:2021
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Universidade da Madeira
Idioma:inglês
Origem:DigitUMa - Repositório da Universidade da Madeira
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author Gharehgazlou, Avideh
author2 Freitas, Carina
Ameis, Stephanie H
Taylor, Margot J.
Lerch, Jason P.
Radua, Joaquim
Anagnostou, Evdokia
author2_role author
author
author
author
author
author
author_facet Gharehgazlou, Avideh
Gharehgazlou, Avideh
Freitas, Carina
Ameis, Stephanie H
Taylor, Margot J.
Lerch, Jason P.
Radua, Joaquim
Anagnostou, Evdokia
Freitas, Carina
Ameis, Stephanie H
Taylor, Margot J.
Lerch, Jason P.
Radua, Joaquim
Anagnostou, Evdokia
author_role author
contributor_name_str_mv DigitUMa
country_str PT
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datacite.contributors.contributor.contributorName.fl_str_mv DigitUMa
datacite.creators.creator.creatorName.fl_str_mv Gharehgazlou, Avideh
Freitas, Carina
Ameis, Stephanie H
Taylor, Margot J.
Lerch, Jason P.
Radua, Joaquim
Anagnostou, Evdokia
datacite.date.Accepted.fl_str_mv 2021-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2022-06-09T11:08:31Z
datacite.date.embargoed.fl_str_mv 2022-06-09T11:08:31Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Attention-deficit hyperactivity disorder
Autism spectrum disorder
Cortical gyrification
lGI
Structural MRI
.
Faculdade de Ciências da Vida
datacite.titles.title.fl_str_mv Cortical gyrification morphology in individuals with ASD and ADHD across the lifespan: a systematic review and meta-analysis
dc.contributor.none.fl_str_mv DigitUMa
dc.creator.none.fl_str_mv Gharehgazlou, Avideh
Freitas, Carina
Ameis, Stephanie H
Taylor, Margot J.
Lerch, Jason P.
Radua, Joaquim
Anagnostou, Evdokia
dc.date.Accepted.fl_str_mv 2021-01-01T00:00:00Z
dc.date.available.fl_str_mv 2022-06-09T11:08:31Z
dc.date.embargoed.fl_str_mv 2022-06-09T11:08:31Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10400.13/4322
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Oxford University Press
dc.rights.cclincense.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Attention-deficit hyperactivity disorder
Autism spectrum disorder
Cortical gyrification
lGI
Structural MRI
.
Faculdade de Ciências da Vida
dc.title.fl_str_mv Cortical gyrification morphology in individuals with ASD and ADHD across the lifespan: a systematic review and meta-analysis
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description Autism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD) are common neurodevelopmental disorders (NDDs) that may impact brain maturation. A number of studies have examined cortical gyrification morphology in both NDDs. Here we review and when possible pool their results to better understand the shared and potentially disorder-specific gyrification features. We searched MEDLINE, PsycINFO, and EMBASE databases, and 24 and 10 studies met the criteria to be included in the systematic review and meta-analysis portions, respectively. Meta-analysis of local Gyrification Index (lGI) findings across ASD studies was conducted with SDM software adapted for surface-based morphometry studies. Meta-regressions were used to explore effects of age, sex, and sample size on gyrification differences. There were no significant differences in gyrification across groups. Qualitative synthesis of remaining ASD studies highlighted heterogeneity in findings. Large-scale ADHD studies reported no differences in gyrification between cases and controls suggesting that, similar to ASD, there is currently no evidence of differences in gyrification morphology compared with controls. Larger, longitudinal studies are needed to further clarify the effects of age, sex, and IQ on cortical gyrification in these NDDs.
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person_str_mv Gharehgazlou, Avideh
Freitas, Carina
Freitas, Carina
https://www.ciencia-id.pt/1616-9C71-0359
1616-9C71-0359
http://orcid.org/0000-0002-3713-9386
0000-0002-3713-9386
Ameis, Stephanie H
Taylor, Margot J.
Lerch, Jason P.
Radua, Joaquim
Anagnostou, Evdokia
publishDate 2021
publisher.none.fl_str_mv Oxford University Press
reponame_str DigitUMa - Repositório da Universidade da Madeira
repository_id_str urn:repositoryAcronym:digituma
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spelling engOxford University Presspt_PTAutism spectrum disorder (ASD) and attention-deficit hyperactivity disorder (ADHD) are common neurodevelopmental disorders (NDDs) that may impact brain maturation. A number of studies have examined cortical gyrification morphology in both NDDs. Here we review and when possible pool their results to better understand the shared and potentially disorder-specific gyrification features. We searched MEDLINE, PsycINFO, and EMBASE databases, and 24 and 10 studies met the criteria to be included in the systematic review and meta-analysis portions, respectively. Meta-analysis of local Gyrification Index (lGI) findings across ASD studies was conducted with SDM software adapted for surface-based morphometry studies. Meta-regressions were used to explore effects of age, sex, and sample size on gyrification differences. There were no significant differences in gyrification across groups. Qualitative synthesis of remaining ASD studies highlighted heterogeneity in findings. Large-scale ADHD studies reported no differences in gyrification between cases and controls suggesting that, similar to ASD, there is currently no evidence of differences in gyrification morphology compared with controls. Larger, longitudinal studies are needed to further clarify the effects of age, sex, and IQ on cortical gyrification in these NDDs.application/pdfpt_PTCortical gyrification morphology in individuals with ASD and ADHD across the lifespan: a systematic review and meta-analysisGharehgazlou, AvidehPersonalFreitas, CarinaDSpacehttp://dspace.org/items/2caaa44a-cb70-4016-ade0-2426574e24dfDSpacehttp://dspace.org/items/2caaa44a-cb70-4016-ade0-2426574e24dfDe Barros FreitasCarina PatríciaCiência IDhttps://www.ciencia-id.pt1616-9C71-0359ORCIDhttp://orcid.org0000-0002-3713-9386Ameis, Stephanie HTaylor, Margot J.Lerch, Jason P.Radua, JoaquimAnagnostou, EvdokiaHostingInstitutionOrganizationalDigitUMae-mailmailto:digituma@uma.ptdigituma@uma.ptDOIIsPartOf10.1093/cercor/bhaa3812022-06-09T11:08:31Z20212021-01-01T00:00:00ZHandlehttp://hdl.handle.net/10400.13/4322http://purl.org/coar/access_right/c_abf2open accessAttention-deficit hyperactivity disorderAutism spectrum disorderCortical gyrificationlGIStructural MRI.Faculdade de Ciências da Vida636269 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal article2021http://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://digituma.uma.pt/bitstreams/8f178af6-6c78-490c-9439-5a4447e1a1fc/downloadCerebral Cortex31526532669
spellingShingle Cortical gyrification morphology in individuals with ASD and ADHD across the lifespan: a systematic review and meta-analysis
Cortical gyrification morphology in individuals with ASD and ADHD across the lifespan: a systematic review and meta-analysis
Gharehgazlou, Avideh
Attention-deficit hyperactivity disorder
Autism spectrum disorder
Cortical gyrification
lGI
Structural MRI
.
Faculdade de Ciências da Vida
Gharehgazlou, Avideh
Attention-deficit hyperactivity disorder
Autism spectrum disorder
Cortical gyrification
lGI
Structural MRI
.
Faculdade de Ciências da Vida
status NEW
subject.fl_str_mv Attention-deficit hyperactivity disorder
Autism spectrum disorder
Cortical gyrification
lGI
Structural MRI
.
Faculdade de Ciências da Vida
title Cortical gyrification morphology in individuals with ASD and ADHD across the lifespan: a systematic review and meta-analysis
title_full Cortical gyrification morphology in individuals with ASD and ADHD across the lifespan: a systematic review and meta-analysis
title_fullStr Cortical gyrification morphology in individuals with ASD and ADHD across the lifespan: a systematic review and meta-analysis
Cortical gyrification morphology in individuals with ASD and ADHD across the lifespan: a systematic review and meta-analysis
title_full_unstemmed Cortical gyrification morphology in individuals with ASD and ADHD across the lifespan: a systematic review and meta-analysis
Cortical gyrification morphology in individuals with ASD and ADHD across the lifespan: a systematic review and meta-analysis
title_short Cortical gyrification morphology in individuals with ASD and ADHD across the lifespan: a systematic review and meta-analysis
title_sort Cortical gyrification morphology in individuals with ASD and ADHD across the lifespan: a systematic review and meta-analysis
topic Attention-deficit hyperactivity disorder
Autism spectrum disorder
Cortical gyrification
lGI
Structural MRI
.
Faculdade de Ciências da Vida
topic_facet Attention-deficit hyperactivity disorder
Autism spectrum disorder
Cortical gyrification
lGI
Structural MRI
.
Faculdade de Ciências da Vida
url http://hdl.handle.net/10400.13/4322
visible 1