Publicação
Stepwise functional evolution in a fungal sugar transporter family
| Resumo: | "Sugar transport is of the utmost importance for most cells and is important to a wide range of applied fields. However, despite the straightforward in silico assignment of many novel transporters, including sugar porters, to existing families, their exact biological role and evolutionary trajectory often remain unclear, mainly because biochemical characterization of membrane proteins is inherently challenging, but also owing to their uncommonly turbulent evolutionary histories. In addition, many important shifts in membrane carrier function are apparently ancient, which further limits our ability to reconstruct evolutionary trajectories in a reliable manner. |
|---|---|
| Autores principais: | Gonçalves, Carla |
| Outros Autores: | Coelho, Mauro A.; Salema-Oom, Madalena; Gonçalves, Paula |
| Assunto: | Fructose transport Yeast metabolic evolution Horizontal gene transfer Ffz DHA1 |
| Ano: | 2016 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Egas Moniz - Cooperativa de Ensino Superior, CRL |
| Idioma: | inglês |
| Origem: | Egas Moniz - Cooperativa de Ensino Superior, CRL |
| _version_ | 1868695814835011584 |
|---|---|
| author | Gonçalves, Carla |
| author2 | Coelho, Mauro A. Salema-Oom, Madalena Gonçalves, Paula |
| author2_role | author author author |
| author_facet | Gonçalves, Carla Coelho, Mauro A. Salema-Oom, Madalena Gonçalves, Paula |
| author_role | author |
| contributor_name_str_mv | Repositório Comum |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Gonçalves, Carla\"},{\"Person.name\":\"Coelho, Mauro A.\"},{\"Person.name\":\"Salema-Oom, Madalena\"},{\"Person.name\":\"Gonçalves, Paula\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Repositório Comum |
| datacite.creators.creator.creatorName.fl_str_mv | Gonçalves, Carla Coelho, Mauro A. Salema-Oom, Madalena Gonçalves, Paula |
| datacite.date.Accepted.fl_str_mv | 2016-02-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2017-03-01T01:30:10Z |
| datacite.date.embargoed.fl_str_mv | 2017-03-01T01:30:10Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Fructose transport Yeast metabolic evolution Horizontal gene transfer Ffz DHA1 |
| datacite.titles.title.fl_str_mv | Stepwise functional evolution in a fungal sugar transporter family |
| dc.contributor.none.fl_str_mv | Repositório Comum |
| dc.creator.none.fl_str_mv | Gonçalves, Carla Coelho, Mauro A. Salema-Oom, Madalena Gonçalves, Paula |
| dc.date.Accepted.fl_str_mv | 2016-02-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2017-03-01T01:30:10Z |
| dc.date.embargoed.fl_str_mv | 2017-03-01T01:30:10Z |
| dc.format.none.fl_str_mv | application/pdf application/pdf |
| dc.identifier.none.fl_str_mv | http://hdl.handle.net/10400.26/17556 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Oxford University Press |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Fructose transport Yeast metabolic evolution Horizontal gene transfer Ffz DHA1 |
| dc.title.fl_str_mv | Stepwise functional evolution in a fungal sugar transporter family |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | "Sugar transport is of the utmost importance for most cells and is important to a wide range of applied fields. However, despite the straightforward in silico assignment of many novel transporters, including sugar porters, to existing families, their exact biological role and evolutionary trajectory often remain unclear, mainly because biochemical characterization of membrane proteins is inherently challenging, but also owing to their uncommonly turbulent evolutionary histories. In addition, many important shifts in membrane carrier function are apparently ancient, which further limits our ability to reconstruct evolutionary trajectories in a reliable manner. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| fulltext.url.fl_str_mv | https://comum.rcaap.pt/bitstreams/1a551ac6-e758-4f4f-be07-f426b12f0a1f/download |
| funding.funder.alternateName_str_mv | FCT |
| funding.funder.identifier_str_mv | http://doi.org/10.13039/501100001871 |
| funding.funder.name_str_mv | Fundação para a Ciência e a Tecnologia |
| funding.name_str_mv | 3599-PPCDT |
| id | em_38e49afd11f5adaf4f39edf133561ba9 |
| identifier.url.fl_str_mv | http://hdl.handle.net/10400.26/17556 |
| instacron_str | em |
| institution | Egas Moniz - Cooperativa de Ensino Superior, CRL |
| instname_str | Egas Moniz - Cooperativa de Ensino Superior, CRL |
| language | eng |
| network_acronym_str | em |
| network_name_str | Egas Moniz - Cooperativa de Ensino Superior, CRL |
| oai_identifier_str | oai:comum.rcaap.pt:10400.26/17556 |
| organization_str_mv | urn:organizationAcronym:em |
| person_str_mv | Gonçalves, Carla Coelho, Mauro A. Salema-Oom, Madalena Gonçalves, Paula |
| publishDate | 2016 |
| publisher.none.fl_str_mv | Oxford University Press |
| reponame_str | Egas Moniz - Cooperativa de Ensino Superior, CRL |
| repository_id_str | urn:repositoryAcronym:em |
| service_str_mv | urn:repositoryAcronym:em |
| spelling | engOxford University Presspt_PT"Sugar transport is of the utmost importance for most cells and is important to a wide range of applied fields. However, despite the straightforward in silico assignment of many novel transporters, including sugar porters, to existing families, their exact biological role and evolutionary trajectory often remain unclear, mainly because biochemical characterization of membrane proteins is inherently challenging, but also owing to their uncommonly turbulent evolutionary histories. In addition, many important shifts in membrane carrier function are apparently ancient, which further limits our ability to reconstruct evolutionary trajectories in a reliable manner.application/pdfapplication/pdfpt_PTStepwise functional evolution in a fungal sugar transporter familyGonçalves, CarlaCoelho, Mauro A.Salema-Oom, MadalenaGonçalves, PaulaHostingInstitutionOrganizationalRepositório Comume-mailmailto:comum@rcaap.ptcomum@rcaap.ptISSNIsPartOf1537-1719ISSNIsPartOf0737-4038DOIIsPartOf10.1093/molbev/msv2202017-03-01T01:30:10Z2016-022016-02-01T00:00:00ZHandlehttp://hdl.handle.net/10400.26/17556http://purl.org/coar/access_right/c_abf2open accessFructose transportYeast metabolic evolutionHorizontal gene transferFfzDHA13028125 bytes3089796 bytesFundação para a Ciência e a TecnologiaImprovement of fructose fermentation by industrial Saccharomyces cerevisiae strains3599-PPCDTCrossref Funder IDhttp://doi.org/10.13039/501100001871literaturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://comum.rcaap.pt/bitstreams/1a551ac6-e758-4f4f-be07-f426b12f0a1f/downloadhttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://comum.rcaap.pt/bitstreams/4480bc1c-cd70-48a6-b08c-0b7d26ee2fa7/downloadMolecular Biology and Evolution33(2)352366 |
| spellingShingle | Stepwise functional evolution in a fungal sugar transporter family Gonçalves, Carla Fructose transport Yeast metabolic evolution Horizontal gene transfer Ffz DHA1 |
| status | SINGLETON |
| subject.fl_str_mv | Fructose transport Yeast metabolic evolution Horizontal gene transfer Ffz DHA1 |
| title | Stepwise functional evolution in a fungal sugar transporter family |
| title_full | Stepwise functional evolution in a fungal sugar transporter family |
| title_fullStr | Stepwise functional evolution in a fungal sugar transporter family |
| title_full_unstemmed | Stepwise functional evolution in a fungal sugar transporter family |
| title_short | Stepwise functional evolution in a fungal sugar transporter family |
| title_sort | Stepwise functional evolution in a fungal sugar transporter family |
| topic | Fructose transport Yeast metabolic evolution Horizontal gene transfer Ffz DHA1 |
| topic_facet | Fructose transport Yeast metabolic evolution Horizontal gene transfer Ffz DHA1 |
| url | http://hdl.handle.net/10400.26/17556 |
| visible | 1 |