Publicação
Marking Techniques for Targeted Axillary Dissection Among Patients With Node-Positive Breast Cancer Treated With Neoadjuvant Chemotherapy
| Resumo: | Invasive breast cancer with axillary lymph node (LN) invasion is a continuing problem worldwide. The morbidity associated with axillary LN dissection along with the high rate of nodal downstaging after neoadjuvant chemotherapy (NACT) made the standard treatment shift towards less invasive surgery. Sentinel lymph node biopsy (SLNB) after NACT is associated with high false-negative rates (13%-14%). To overcome this problem, it was concluded that the positive nodes should first be indicated with image-detectable markers and then removed together with SLNB: targeted axillary dissection (TAD). This review aims to describe and evaluate the different marking techniques for TAD in patients with node-positive breast cancer treated with NACT, namely: clip placement and guidewire localization; clip placement and 125I-labelled radioactive seed localization; clip placement and skin mark; clip placement and intraoperative ultrasound; tattooing with a sterile black carbon suspension; magnetic seeds; radar and infrared light technology localization. Targeted axillary dissection techniques have shown false-negative rates below 9% and identification rates above 95%. The most studied technique is guidewire localization, as it is also the oldest one. However, according to data gathered from this review, some newer techniques have shown to be very promising due to their statistical results and management factors. |
|---|---|
| Autores principais: | Gante, Inês |
| Outros Autores: | Maldonado, João Pedro; Dias, Margarida Figueiredo |
| Assunto: | Breast neoplasms lymphatic metastasis neoadjuvant therapy targeted axillary dissection |
| Ano: | 2023 |
| País: | Portugal |
| Tipo de documento: | artigo |
| Tipo de acesso: | acesso aberto |
| Instituição associada: | Universidade de Coimbra |
| Idioma: | inglês |
| Origem: | Estudo Geral - Universidade de Coimbra |
| _version_ | 1868797735988101120 |
|---|---|
| author | Gante, Inês |
| author2 | Maldonado, João Pedro Dias, Margarida Figueiredo |
| author2_role | author author |
| author_facet | Gante, Inês Maldonado, João Pedro Dias, Margarida Figueiredo |
| author_role | author |
| contributor_name_str_mv | Estudo Geral |
| country_str | PT |
| creators_json_txt | [{\"Person.name\":\"Gante, Inês\"},{\"Person.name\":\"Maldonado, João Pedro\"},{\"Person.name\":\"Dias, Margarida Figueiredo\"}] |
| datacite.contributors.contributor.contributorName.fl_str_mv | Estudo Geral |
| datacite.creators.creator.creatorName.fl_str_mv | Gante, Inês Maldonado, João Pedro Dias, Margarida Figueiredo |
| datacite.date.Accepted.fl_str_mv | 2023-01-01T00:00:00Z |
| datacite.date.available.fl_str_mv | 2023-01-01T00:00:00Z |
| datacite.rights.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| datacite.subjects.subject.fl_str_mv | Breast neoplasms lymphatic metastasis neoadjuvant therapy targeted axillary dissection |
| datacite.titles.title.fl_str_mv | Marking Techniques for Targeted Axillary Dissection Among Patients With Node-Positive Breast Cancer Treated With Neoadjuvant Chemotherapy |
| dc.contributor.none.fl_str_mv | Estudo Geral |
| dc.creator.none.fl_str_mv | Gante, Inês Maldonado, João Pedro Dias, Margarida Figueiredo |
| dc.date.Accepted.fl_str_mv | 2023-01-01T00:00:00Z |
| dc.date.available.fl_str_mv | 2023-01-01T00:00:00Z |
| dc.format.none.fl_str_mv | application/pdf |
| dc.identifier.none.fl_str_mv | https://hdl.handle.net/10316/114410 |
| dc.language.none.fl_str_mv | eng |
| dc.publisher.none.fl_str_mv | Libertas Academica |
| dc.rights.none.fl_str_mv | http://purl.org/coar/access_right/c_abf2 |
| dc.subject.none.fl_str_mv | Breast neoplasms lymphatic metastasis neoadjuvant therapy targeted axillary dissection |
| dc.title.fl_str_mv | Marking Techniques for Targeted Axillary Dissection Among Patients With Node-Positive Breast Cancer Treated With Neoadjuvant Chemotherapy |
| dc.type.none.fl_str_mv | http://purl.org/coar/resource_type/c_6501 |
| description | Invasive breast cancer with axillary lymph node (LN) invasion is a continuing problem worldwide. The morbidity associated with axillary LN dissection along with the high rate of nodal downstaging after neoadjuvant chemotherapy (NACT) made the standard treatment shift towards less invasive surgery. Sentinel lymph node biopsy (SLNB) after NACT is associated with high false-negative rates (13%-14%). To overcome this problem, it was concluded that the positive nodes should first be indicated with image-detectable markers and then removed together with SLNB: targeted axillary dissection (TAD). This review aims to describe and evaluate the different marking techniques for TAD in patients with node-positive breast cancer treated with NACT, namely: clip placement and guidewire localization; clip placement and 125I-labelled radioactive seed localization; clip placement and skin mark; clip placement and intraoperative ultrasound; tattooing with a sterile black carbon suspension; magnetic seeds; radar and infrared light technology localization. Targeted axillary dissection techniques have shown false-negative rates below 9% and identification rates above 95%. The most studied technique is guidewire localization, as it is also the oldest one. However, according to data gathered from this review, some newer techniques have shown to be very promising due to their statistical results and management factors. |
| dirty | 0 |
| eu_rights_str_mv | openAccess |
| format | article |
| id | estudogl_2ed3d9cdee7fc2c6ea366b3a6ad4d3bf |
| identifier.url.fl_str_mv | https://hdl.handle.net/10316/114410 |
| instacron_str | uc |
| institution | Universidade de Coimbra |
| instname_str | Universidade de Coimbra |
| language | eng |
| network_acronym_str | estudogl |
| network_name_str | Estudo Geral - Universidade de Coimbra |
| oai_identifier_str | oai:estudogeral.uc.pt:10316/114410 |
| organization_str_mv | urn:organizationAcronym:uc |
| person_str_mv | Gante, Inês Maldonado, João Pedro Dias, Margarida Figueiredo |
| publishDate | 2023 |
| publisher.none.fl_str_mv | Libertas Academica |
| reponame_str | Estudo Geral - Universidade de Coimbra |
| repository_id_str | urn:repositoryAcronym:estudogl |
| service_str_mv | urn:repositoryAcronym:estudogl |
| spelling | engLibertas AcademicaengInvasive breast cancer with axillary lymph node (LN) invasion is a continuing problem worldwide. The morbidity associated with axillary LN dissection along with the high rate of nodal downstaging after neoadjuvant chemotherapy (NACT) made the standard treatment shift towards less invasive surgery. Sentinel lymph node biopsy (SLNB) after NACT is associated with high false-negative rates (13%-14%). To overcome this problem, it was concluded that the positive nodes should first be indicated with image-detectable markers and then removed together with SLNB: targeted axillary dissection (TAD). This review aims to describe and evaluate the different marking techniques for TAD in patients with node-positive breast cancer treated with NACT, namely: clip placement and guidewire localization; clip placement and 125I-labelled radioactive seed localization; clip placement and skin mark; clip placement and intraoperative ultrasound; tattooing with a sterile black carbon suspension; magnetic seeds; radar and infrared light technology localization. Targeted axillary dissection techniques have shown false-negative rates below 9% and identification rates above 95%. The most studied technique is guidewire localization, as it is also the oldest one. However, according to data gathered from this review, some newer techniques have shown to be very promising due to their statistical results and management factors.application/pdfporMarking Techniques for Targeted Axillary Dissection Among Patients With Node-Positive Breast Cancer Treated With Neoadjuvant ChemotherapyGante, InêsMaldonado, João PedroDias, Margarida FigueiredoHostingInstitutionOrganizationalEstudo Gerale-mailmailto:inf@sib.uc.ptinf@sib.uc.ptISSNIsPartOf1178-2234DOIIsPartOf10.1177/1178223423117615920232023-01-01T00:00:00Z2023-01-01T00:00:00ZHandlehttps://hdl.handle.net/10316/114410http://purl.org/coar/access_right/c_abf2open accessBreast neoplasmslymphatic metastasisneoadjuvant therapytargeted axillary dissection221787 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articleapplication/pdfhttps://estudogeral.uc.pt/bitstream/10316/114410/1/Marking-Techniques-for-Targeted-Axillary-Dissection-Among-Patients-With-NodePositive-Breast-Cancer-Treated-With-Neoadjuvant-ChemotherapyBreast-Cancer-Basic-and-Clinical-Research.pdf |
| spellingShingle | Marking Techniques for Targeted Axillary Dissection Among Patients With Node-Positive Breast Cancer Treated With Neoadjuvant Chemotherapy Gante, Inês Breast neoplasms lymphatic metastasis neoadjuvant therapy targeted axillary dissection |
| status | SINGLETON |
| subject.fl_str_mv | Breast neoplasms lymphatic metastasis neoadjuvant therapy targeted axillary dissection |
| title | Marking Techniques for Targeted Axillary Dissection Among Patients With Node-Positive Breast Cancer Treated With Neoadjuvant Chemotherapy |
| title_full | Marking Techniques for Targeted Axillary Dissection Among Patients With Node-Positive Breast Cancer Treated With Neoadjuvant Chemotherapy |
| title_fullStr | Marking Techniques for Targeted Axillary Dissection Among Patients With Node-Positive Breast Cancer Treated With Neoadjuvant Chemotherapy |
| title_full_unstemmed | Marking Techniques for Targeted Axillary Dissection Among Patients With Node-Positive Breast Cancer Treated With Neoadjuvant Chemotherapy |
| title_short | Marking Techniques for Targeted Axillary Dissection Among Patients With Node-Positive Breast Cancer Treated With Neoadjuvant Chemotherapy |
| title_sort | Marking Techniques for Targeted Axillary Dissection Among Patients With Node-Positive Breast Cancer Treated With Neoadjuvant Chemotherapy |
| topic | Breast neoplasms lymphatic metastasis neoadjuvant therapy targeted axillary dissection |
| topic_facet | Breast neoplasms lymphatic metastasis neoadjuvant therapy targeted axillary dissection |
| url | https://hdl.handle.net/10316/114410 |
| visible | 1 |