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Folic Acid Levels in a Sample of Portuguese Psychiatric Outpatients

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Resumo:INTRODUCTION: There is substantial evidence of the association between mental disorders and low folic acid levels. The aim of this study was to evaluate the prevalence of folic acid deficiency in a sample of Portuguese psychiatric outpatients. METHODS: The study was retrospective and included 428 psychiatric outpatients with a diagnosis of depression or non-affective psychosis, for whom folic acid levels had been measured as part of routine blood tests. Folic acid levels from other hospital patients from the same time period were also registered. RESULTS AND DISCUSSION: The prevalence of folic acid deficiency in this sample is 18%. Non-psychiatric hospital patients with risk factors for folic acid deficiency have a prevalence of 15% of folic acid deficiency. Men and younger patients have lower folic acid levels, with statistical significance, and the prevalence of deficit reached 26%. CONCLUSION: The elevated frequency of folic acid deficiency in this sample of patients shows that folic acid levels should be routinely assessed in every patient with depression or psychosis, in order to avoid maintenance of symptoms and treatment resistance
Autores principais:Abreu-Lopes, J
Assunto:Ácido Fólico Deficiência de Ácido Fólico Depressão Transtornos Psicóticos
Ano:2016
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso aberto
Instituição associada:Hospital de Vila Franca de Xira
Idioma:inglês
Origem:Hospital de Vila Franca de Xira
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author Abreu-Lopes, J
author_facet Abreu-Lopes, J
author_role author
contributor_name_str_mv Repositório Comum
country_str PT
creators_json_txt [{\"Person.name\":\"Abreu-Lopes, J\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Repositório Comum
datacite.creators.creator.creatorName.fl_str_mv Abreu-Lopes, J
datacite.date.Accepted.fl_str_mv 2016-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2016-11-06T18:51:06Z
datacite.date.embargoed.fl_str_mv 2016-11-06T18:51:06Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Ácido Fólico
Deficiência de Ácido Fólico
Depressão
Transtornos Psicóticos
datacite.titles.title.fl_str_mv Folic Acid Levels in a Sample of Portuguese Psychiatric Outpatients
Níveis de Ácido Fólico numa Amostra de Doentes Psiquiátricos Portugueses em Ambulatório
dc.contributor.none.fl_str_mv Repositório Comum
dc.creator.none.fl_str_mv Abreu-Lopes, J
dc.date.Accepted.fl_str_mv 2016-01-01T00:00:00Z
dc.date.available.fl_str_mv 2016-11-06T18:51:06Z
dc.date.embargoed.fl_str_mv 2016-11-06T18:51:06Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10400.26/15302
dc.language.none.fl_str_mv eng
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Ácido Fólico
Deficiência de Ácido Fólico
Depressão
Transtornos Psicóticos
dc.title.fl_str_mv Folic Acid Levels in a Sample of Portuguese Psychiatric Outpatients
Níveis de Ácido Fólico numa Amostra de Doentes Psiquiátricos Portugueses em Ambulatório
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description INTRODUCTION: There is substantial evidence of the association between mental disorders and low folic acid levels. The aim of this study was to evaluate the prevalence of folic acid deficiency in a sample of Portuguese psychiatric outpatients. METHODS: The study was retrospective and included 428 psychiatric outpatients with a diagnosis of depression or non-affective psychosis, for whom folic acid levels had been measured as part of routine blood tests. Folic acid levels from other hospital patients from the same time period were also registered. RESULTS AND DISCUSSION: The prevalence of folic acid deficiency in this sample is 18%. Non-psychiatric hospital patients with risk factors for folic acid deficiency have a prevalence of 15% of folic acid deficiency. Men and younger patients have lower folic acid levels, with statistical significance, and the prevalence of deficit reached 26%. CONCLUSION: The elevated frequency of folic acid deficiency in this sample of patients shows that folic acid levels should be routinely assessed in every patient with depression or psychosis, in order to avoid maintenance of symptoms and treatment resistance
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person_str_mv Abreu-Lopes, J
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spelling engpt_PTINTRODUCTION: There is substantial evidence of the association between mental disorders and low folic acid levels. The aim of this study was to evaluate the prevalence of folic acid deficiency in a sample of Portuguese psychiatric outpatients. METHODS: The study was retrospective and included 428 psychiatric outpatients with a diagnosis of depression or non-affective psychosis, for whom folic acid levels had been measured as part of routine blood tests. Folic acid levels from other hospital patients from the same time period were also registered. RESULTS AND DISCUSSION: The prevalence of folic acid deficiency in this sample is 18%. Non-psychiatric hospital patients with risk factors for folic acid deficiency have a prevalence of 15% of folic acid deficiency. Men and younger patients have lower folic acid levels, with statistical significance, and the prevalence of deficit reached 26%. CONCLUSION: The elevated frequency of folic acid deficiency in this sample of patients shows that folic acid levels should be routinely assessed in every patient with depression or psychosis, in order to avoid maintenance of symptoms and treatment resistanceapplication/pdfpt_PTFolic Acid Levels in a Sample of Portuguese Psychiatric OutpatientsAlternativeTitlept_PTNíveis de Ácido Fólico numa Amostra de Doentes Psiquiátricos Portugueses em AmbulatórioAbreu-Lopes, JHostingInstitutionOrganizationalRepositório Comume-mailmailto:comum@rcaap.ptcomum@rcaap.pt2016-11-06T18:51:06Z20162016-01-01T00:00:00ZHandlehttp://hdl.handle.net/10400.26/15302http://purl.org/coar/access_right/c_abf2open accessÁcido FólicoDeficiência de Ácido FólicoDepressãoTranstornos Psicóticos231637 bytesliteraturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://comum.rcaap.pt/bitstreams/170463af-45c1-45fa-9b2f-d5bebe950601/download
spellingShingle Folic Acid Levels in a Sample of Portuguese Psychiatric Outpatients
Abreu-Lopes, J
Ácido Fólico
Deficiência de Ácido Fólico
Depressão
Transtornos Psicóticos
status SINGLETON
subject.fl_str_mv Ácido Fólico
Deficiência de Ácido Fólico
Depressão
Transtornos Psicóticos
title Folic Acid Levels in a Sample of Portuguese Psychiatric Outpatients
title_full Folic Acid Levels in a Sample of Portuguese Psychiatric Outpatients
title_fullStr Folic Acid Levels in a Sample of Portuguese Psychiatric Outpatients
title_full_unstemmed Folic Acid Levels in a Sample of Portuguese Psychiatric Outpatients
title_short Folic Acid Levels in a Sample of Portuguese Psychiatric Outpatients
title_sort Folic Acid Levels in a Sample of Portuguese Psychiatric Outpatients
topic Ácido Fólico
Deficiência de Ácido Fólico
Depressão
Transtornos Psicóticos
topic_facet Ácido Fólico
Deficiência de Ácido Fólico
Depressão
Transtornos Psicóticos
url http://hdl.handle.net/10400.26/15302
visible 1