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A particle method computer simulation: applications to the study of blood flow

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Resumo:The need to analyse the microscopic mechanical behaviour of blood flow was one of the main reasons to develop a new computer simulation using a particle method. This new mesh free method is based on a moving-particle semi-implicit (MPS) method, which has been developed to simulate incompressible fluids based on the Navier-Stokes equations. The simulation region was discretized by particles that moves in Lagrangian coordinates, where the plasma and platelets were modelled as fluid particles, red blood cells (RBC) as elastic particles and vessel wall as rigid particles. In this paper, some applications of the MPS method to study the blood flow are briefly analysed, such as the motion and deformation of red blood cells (RBC) in plasma flow and the platelet aggregation process in blood flow. Some preliminary studies suggest that there is evidence that the proposed method enables the analysis of the RBC motion and deformation in the plasma flow and also the initial thrombogenesis, growth and destruction of thrombus.
Autores principais:Lima, Rui A.
Outros Autores:Kitagawa, Yoshitaka; Kamada, Hiroki; Tsubota, Ken-ichi; Wada, Shigeo; Yamaguchi, Takami
Assunto:Particle method Blood flow MPS method Red blood cells
Ano:2005
País:Portugal
Tipo de documento:comunicação em conferência
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
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author Lima, Rui A.
author2 Kitagawa, Yoshitaka
Kamada, Hiroki
Tsubota, Ken-ichi
Wada, Shigeo
Yamaguchi, Takami
author2_role author
author
author
author
author
author_facet Lima, Rui A.
Kitagawa, Yoshitaka
Kamada, Hiroki
Tsubota, Ken-ichi
Wada, Shigeo
Yamaguchi, Takami
author_role author
contributor_name_str_mv Biblioteca Digital do IPB
country_str PT
creators_json_txt [{\"Person.name\":\"Lima, Rui A.\",\"Person.identifier.orcid\":\"0000-0003-3428-637X\"},{\"Person.name\":\"Kitagawa, Yoshitaka\"},{\"Person.name\":\"Kamada, Hiroki\"},{\"Person.name\":\"Tsubota, Ken-ichi\"},{\"Person.name\":\"Wada, Shigeo\"},{\"Person.name\":\"Yamaguchi, Takami\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Biblioteca Digital do IPB
datacite.creators.creator.creatorName.fl_str_mv Lima, Rui A.
Kitagawa, Yoshitaka
Kamada, Hiroki
Tsubota, Ken-ichi
Wada, Shigeo
Yamaguchi, Takami
datacite.date.Accepted.fl_str_mv 2005-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2010-02-09T10:28:14Z
datacite.date.embargoed.fl_str_mv 2010-02-09T10:28:14Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_abf2
datacite.subjects.subject.fl_str_mv Particle method
Blood flow
MPS method
Red blood cells
datacite.titles.title.fl_str_mv A particle method computer simulation: applications to the study of blood flow
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.creator.none.fl_str_mv Lima, Rui A.
Kitagawa, Yoshitaka
Kamada, Hiroki
Tsubota, Ken-ichi
Wada, Shigeo
Yamaguchi, Takami
dc.date.Accepted.fl_str_mv 2005-01-01T00:00:00Z
dc.date.available.fl_str_mv 2010-02-09T10:28:14Z
dc.date.embargoed.fl_str_mv 2010-02-09T10:28:14Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10198/1784
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Biomecânica
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Particle method
Blood flow
MPS method
Red blood cells
dc.title.fl_str_mv A particle method computer simulation: applications to the study of blood flow
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_5794
description The need to analyse the microscopic mechanical behaviour of blood flow was one of the main reasons to develop a new computer simulation using a particle method. This new mesh free method is based on a moving-particle semi-implicit (MPS) method, which has been developed to simulate incompressible fluids based on the Navier-Stokes equations. The simulation region was discretized by particles that moves in Lagrangian coordinates, where the plasma and platelets were modelled as fluid particles, red blood cells (RBC) as elastic particles and vessel wall as rigid particles. In this paper, some applications of the MPS method to study the blood flow are briefly analysed, such as the motion and deformation of red blood cells (RBC) in plasma flow and the platelet aggregation process in blood flow. Some preliminary studies suggest that there is evidence that the proposed method enables the analysis of the RBC motion and deformation in the plasma flow and also the initial thrombogenesis, growth and destruction of thrombus.
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eu_rights_str_mv openAccess
format conferencePaper
fulltext.url.fl_str_mv https://bibliotecadigital.ipb.pt/bitstreams/e663e28b-847b-450d-967a-1d472eafa063/download
id ipb_0f37807e80d26696295ea8a477fb28af
identifier.url.fl_str_mv http://hdl.handle.net/10198/1784
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institution Instituto Politécnico de Bragança
instname_str Instituto Politécnico de Bragança
language eng
network_acronym_str ipb
network_name_str Biblioteca Digital do IPB
oai_identifier_str oai:bibliotecadigital.ipb.pt:10198/1784
organization_str_mv urn:organizationAcronym:ipb
person_str_mv Lima, Rui A.
Lima, Rui A.
https://www.ciencia-id.pt/EE12-C3FB-349D
EE12-C3FB-349D
http://orcid.org/0000-0003-3428-637X
0000-0003-3428-637X
Kitagawa, Yoshitaka
Kamada, Hiroki
Tsubota, Ken-ichi
Wada, Shigeo
Yamaguchi, Takami
publishDate 2005
publisher.none.fl_str_mv Sociedade Portuguesa de Biomecânica
reponame_str Biblioteca Digital do IPB
repository_id_str urn:repositoryAcronym:ipb
service_str_mv urn:repositoryAcronym:ipb
spelling engSociedade Portuguesa de BiomecânicaptThe need to analyse the microscopic mechanical behaviour of blood flow was one of the main reasons to develop a new computer simulation using a particle method. This new mesh free method is based on a moving-particle semi-implicit (MPS) method, which has been developed to simulate incompressible fluids based on the Navier-Stokes equations. The simulation region was discretized by particles that moves in Lagrangian coordinates, where the plasma and platelets were modelled as fluid particles, red blood cells (RBC) as elastic particles and vessel wall as rigid particles. In this paper, some applications of the MPS method to study the blood flow are briefly analysed, such as the motion and deformation of red blood cells (RBC) in plasma flow and the platelet aggregation process in blood flow. Some preliminary studies suggest that there is evidence that the proposed method enables the analysis of the RBC motion and deformation in the plasma flow and also the initial thrombogenesis, growth and destruction of thrombus.application/pdfptA particle method computer simulation: applications to the study of blood flowPersonalLima, Rui A.DSpacehttp://dspace.org/items/7b50c499-8095-4f4f-8b1b-fa7388e4ff62DSpacehttp://dspace.org/items/7b50c499-8095-4f4f-8b1b-fa7388e4ff62LimaRui A.Ciência IDhttps://www.ciencia-id.ptEE12-C3FB-349DORCIDhttp://orcid.org0000-0003-3428-637XResearcher IDhttps://www.researcherid.comH-5157-2016Scopus Author IDhttps://www.scopus.com18437397800Kitagawa, YoshitakaKamada, HirokiTsubota, Ken-ichiWada, ShigeoYamaguchi, TakamiHostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptISBNIsPartOf972-789-151-92010-02-09T10:28:14Z20052005-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/1784http://purl.org/coar/access_right/c_abf2open accessParticle methodBlood flowMPS methodRed blood cells766211 bytesother research producthttp://purl.org/coar/resource_type/c_5794conference paperhttp://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/e663e28b-847b-450d-967a-1d472eafa063/download1º Encontro de BiomecânicaAbrantes, Portugal
spellingShingle A particle method computer simulation: applications to the study of blood flow
Lima, Rui A.
Particle method
Blood flow
MPS method
Red blood cells
status SINGLETON
subject.fl_str_mv Particle method
Blood flow
MPS method
Red blood cells
title A particle method computer simulation: applications to the study of blood flow
title_full A particle method computer simulation: applications to the study of blood flow
title_fullStr A particle method computer simulation: applications to the study of blood flow
title_full_unstemmed A particle method computer simulation: applications to the study of blood flow
title_short A particle method computer simulation: applications to the study of blood flow
title_sort A particle method computer simulation: applications to the study of blood flow
topic Particle method
Blood flow
MPS method
Red blood cells
topic_facet Particle method
Blood flow
MPS method
Red blood cells
url http://hdl.handle.net/10198/1784
visible 1