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A particle method computer simulation: applications to the study of blood flow

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Resumo:The need to analyse the microscopic mechanical behaviour of blood flow was one of the main reasons to develop a new computer simulation using a particle method. This new mesh free method is based on a moving-particle semi-implicit (MPS) method, which has been developed to simulate incompressible fluids based on the Navier-Stokes equations. The simulation region was discretized by particles that moves in Lagrangian coordinates, where the plasma and platelets were modelled as fluid particles, red blood cells (RBC) as elastic particles and vessel wall as rigid particles. In this paper, some applications of the MPS method to study the blood flow are briefly analysed, such as the motion and deformation of red blood cells (RBC) in plasma flow and the platelet aggregation process in blood flow. Some preliminary studies suggest that there is evidence that the proposed method enables the analysis of the RBC motion and deformation in the plasma flow and also the initial thrombogenesis, growth and destruction of thrombus.
Autores principais:Lima, Rui A.
Outros Autores:Kitagawa, Yoshitaka; Kamada, Hiroki; Tsubota, Ken-ichi; Wada, Shigeo; Yamaguchi, Takami
Assunto:Particle method Blood flow MPS method Red blood cells
Ano:2005
País:Portugal
Tipo de documento:comunicação em conferência
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB

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