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Pieris brassicae inhibits xanthine oxidase.

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Resumo:The antioxidant potential of an aqueous extract obtained from Pieris brassicae larvae reared on Brassica oleracea L. var. costata DC was evaluated against 2,2-diphenyl-1-picrylhydrazyl radical and several reactive oxygen species. The results revealed an effective concentration-dependent protective activity against superoxide and hydroxyl radicals, being superior to that of the host plant. In addition, the larvae extract also exhibited a strong inhibitory effect on xanthine oxidase that was not observed for B. oleracea var. costata. A weak scavenging ability was noticed for hypochlorous acid. Several phenolic compounds with complex chemical structures that are hard to synthesize in the laboratory were found in P. brassicae extract. This is the first time that an insect has been tested for its xanthine oxidase inhibitory capacity, which proved to be very high. These findings are interesting considering that they can be used by food or pharmaceutical industries to prevent the oxidation of their products, to increase the dietary supply of antioxidants, or for prevention of free radical-mediated diseases, namely, gout.
Autores principais:Sousa, Carla
Outros Autores:Pereira, David M.; Valentão, Patrícia; Ferreres, Frederico; Pereira, J.A.; Seabra, Rosa M.; Andrade, Paula B.
Assunto:Pieris brassicae Brassica oleracea var. costata Phenolic compounds Antioxidant activity
Ano:2009
País:Portugal
Tipo de documento:artigo
Tipo de acesso:acesso restrito
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
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author Sousa, Carla
author2 Pereira, David M.
Valentão, Patrícia
Ferreres, Frederico
Pereira, J.A.
Seabra, Rosa M.
Andrade, Paula B.
author2_role author
author
author
author
author
author
author_facet Sousa, Carla
Pereira, David M.
Valentão, Patrícia
Ferreres, Frederico
Pereira, J.A.
Seabra, Rosa M.
Andrade, Paula B.
author_role author
contributor_name_str_mv Biblioteca Digital do IPB
country_str PT
creators_json_txt [{\"Person.name\":\"Sousa, Carla\"},{\"Person.name\":\"Pereira, David M.\"},{\"Person.name\":\"Valentão, Patrícia\"},{\"Person.name\":\"Ferreres, Frederico\"},{\"Person.name\":\"Pereira, J.A.\",\"Person.identifier.orcid\":\"0000-0002-2260-0600\"},{\"Person.name\":\"Seabra, Rosa M.\"},{\"Person.name\":\"Andrade, Paula B.\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Biblioteca Digital do IPB
datacite.creators.creator.creatorName.fl_str_mv Sousa, Carla
Pereira, David M.
Valentão, Patrícia
Ferreres, Frederico
Pereira, J.A.
Seabra, Rosa M.
Andrade, Paula B.
datacite.date.Accepted.fl_str_mv 2009-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2011-01-13T15:42:43Z
datacite.date.embargoed.fl_str_mv 2011-01-13T15:42:43Z
datacite.rights.fl_str_mv http://purl.org/coar/access_right/c_16ec
datacite.subjects.subject.fl_str_mv Pieris brassicae
Brassica oleracea var. costata
Phenolic compounds
Antioxidant activity
datacite.titles.title.fl_str_mv Pieris brassicae inhibits xanthine oxidase.
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.creator.none.fl_str_mv Sousa, Carla
Pereira, David M.
Valentão, Patrícia
Ferreres, Frederico
Pereira, J.A.
Seabra, Rosa M.
Andrade, Paula B.
dc.date.Accepted.fl_str_mv 2009-01-01T00:00:00Z
dc.date.available.fl_str_mv 2011-01-13T15:42:43Z
dc.date.embargoed.fl_str_mv 2011-01-13T15:42:43Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10198/3102
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv ACS
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_16ec
dc.subject.none.fl_str_mv Pieris brassicae
Brassica oleracea var. costata
Phenolic compounds
Antioxidant activity
dc.title.fl_str_mv Pieris brassicae inhibits xanthine oxidase.
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_6501
description The antioxidant potential of an aqueous extract obtained from Pieris brassicae larvae reared on Brassica oleracea L. var. costata DC was evaluated against 2,2-diphenyl-1-picrylhydrazyl radical and several reactive oxygen species. The results revealed an effective concentration-dependent protective activity against superoxide and hydroxyl radicals, being superior to that of the host plant. In addition, the larvae extract also exhibited a strong inhibitory effect on xanthine oxidase that was not observed for B. oleracea var. costata. A weak scavenging ability was noticed for hypochlorous acid. Several phenolic compounds with complex chemical structures that are hard to synthesize in the laboratory were found in P. brassicae extract. This is the first time that an insect has been tested for its xanthine oxidase inhibitory capacity, which proved to be very high. These findings are interesting considering that they can be used by food or pharmaceutical industries to prevent the oxidation of their products, to increase the dietary supply of antioxidants, or for prevention of free radical-mediated diseases, namely, gout.
dirty 0
eu_rights_str_mv restrictedAccess
format article
fulltext.url.fl_str_mv https://bibliotecadigital.ipb.pt/bitstreams/432acf20-f73e-4782-9dba-99860af6ab88/download
funding.funder.alternateName_str_mv FCT
funding.funder.identifier_str_mv http://doi.org/10.13039/501100001871
funding.funder.name_str_mv Fundação para a Ciência e a Tecnologia
funding.name_str_mv 5876-PPCDTI
id ipb_0f441cb06fe8e4e971d09edb12b1ad21
identifier.url.fl_str_mv http://hdl.handle.net/10198/3102
instacron_str ipb
institution Instituto Politécnico de Bragança
instname_str Instituto Politécnico de Bragança
language eng
network_acronym_str ipb
network_name_str Biblioteca Digital do IPB
oai_identifier_str oai:bibliotecadigital.ipb.pt:10198/3102
organization_str_mv urn:organizationAcronym:ipb
person_str_mv Sousa, Carla
Pereira, David M.
Valentão, Patrícia
Ferreres, Frederico
Pereira, J.A.
Pereira, J.A.
https://www.ciencia-id.pt/611F-80B2-A7C1
611F-80B2-A7C1
http://orcid.org/0000-0002-2260-0600
0000-0002-2260-0600
Seabra, Rosa M.
Andrade, Paula B.
publishDate 2009
publisher.none.fl_str_mv ACS
reponame_str Biblioteca Digital do IPB
repository_id_str urn:repositoryAcronym:ipb
service_str_mv urn:repositoryAcronym:ipb
spelling engACSporThe antioxidant potential of an aqueous extract obtained from Pieris brassicae larvae reared on Brassica oleracea L. var. costata DC was evaluated against 2,2-diphenyl-1-picrylhydrazyl radical and several reactive oxygen species. The results revealed an effective concentration-dependent protective activity against superoxide and hydroxyl radicals, being superior to that of the host plant. In addition, the larvae extract also exhibited a strong inhibitory effect on xanthine oxidase that was not observed for B. oleracea var. costata. A weak scavenging ability was noticed for hypochlorous acid. Several phenolic compounds with complex chemical structures that are hard to synthesize in the laboratory were found in P. brassicae extract. This is the first time that an insect has been tested for its xanthine oxidase inhibitory capacity, which proved to be very high. These findings are interesting considering that they can be used by food or pharmaceutical industries to prevent the oxidation of their products, to increase the dietary supply of antioxidants, or for prevention of free radical-mediated diseases, namely, gout.application/pdfporPieris brassicae inhibits xanthine oxidase.Sousa, CarlaPereira, David M.Valentão, PatríciaFerreres, FredericoPersonalPereira, J.A.DSpacehttp://dspace.org/items/7932162e-a2da-4913-b00d-17babbe51857DSpacehttp://dspace.org/items/7932162e-a2da-4913-b00d-17babbe51857PereiraJosé AlbertoCiência IDhttps://www.ciencia-id.pt611F-80B2-A7C1ORCIDhttp://orcid.org0000-0002-2260-0600Researcher IDhttps://www.researcherid.comL-6798-2014Scopus Author IDhttps://www.scopus.com57204366348Seabra, Rosa M.Andrade, Paula B.HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptISSNIsPartOf0021-8561DOIIsPartOf10.1021/jf803831v2011-01-13T15:42:43Z20092009-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/3102http://purl.org/coar/access_right/c_16ecrestricted accessPieris brassicaeBrassica oleracea var. costataPhenolic compoundsAntioxidant activity649149 bytesFundação para a Ciência e a TecnologiaPieris brassicae as laboratory of synthesis of new compounds with biological potential, starting from Brassica oleracea var. costata, Brassica oleracea var. acephala and Brassica rapa var. rapa.5876-PPCDTICrossref Funder IDhttp://doi.org/10.13039/501100001871literaturehttp://purl.org/coar/resource_type/c_6501journal articlehttp://purl.org/coar/access_right/c_16ecapplication/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/432acf20-f73e-4782-9dba-99860af6ab88/downloadJournal of Agricultural and Food Chemistry5722882294
spellingShingle Pieris brassicae inhibits xanthine oxidase.
Sousa, Carla
Pieris brassicae
Brassica oleracea var. costata
Phenolic compounds
Antioxidant activity
status SINGLETON
subject.fl_str_mv Pieris brassicae
Brassica oleracea var. costata
Phenolic compounds
Antioxidant activity
title Pieris brassicae inhibits xanthine oxidase.
title_full Pieris brassicae inhibits xanthine oxidase.
title_fullStr Pieris brassicae inhibits xanthine oxidase.
title_full_unstemmed Pieris brassicae inhibits xanthine oxidase.
title_short Pieris brassicae inhibits xanthine oxidase.
title_sort Pieris brassicae inhibits xanthine oxidase.
topic Pieris brassicae
Brassica oleracea var. costata
Phenolic compounds
Antioxidant activity
topic_facet Pieris brassicae
Brassica oleracea var. costata
Phenolic compounds
Antioxidant activity
url http://hdl.handle.net/10198/3102
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