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Micro/nanofluidic and lab-on-a-chip devices for biomedical applications

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Resumo:Micro/Nanofluidic and lab-on-a-chip devices have been increasingly used in biomedical research [1]. Because of their adaptability, feasibility, and cost-efficiency, these devices can revolutionize the future of preclinical technologies. Furthermore, they allow insights into the performance and toxic effects of responsive drug delivery nanocarriers to be obtained, which consequently allow the shortcomings of two/three-dimensional static cultures and animal testing to be overcome and help to reduce drug development costs and time [2–4]. With the constant advancements in biomedical technology, the development of enhanced microfluidic devices has accelerated, and numerous models have been reported. Given the multidisciplinary of this Special Issue (SI), papers on different subjects were published making a total of 14 contributions, 10 original research papers, and 4 review papers. The review paper of Ko et al. [1] provides a comprehensive overview of the significant advancements in engineered organ-on-a-chip research in a general way while in the review presented by Kanabekova and colleagues [2], a thorough analysis of microphysiological platforms used for modeling liver diseases can be found. To get a summary of the numerical models of microfluidic organ-on-a-chip devices developed in recent years, the review presented by Carvalho et al. [5] can be read. On the other hand, Maia et al. [6] report a systematic review of the diagnosis methods developed for COVID-19, providing an overview of the advancements made since the start of the pandemic. In the following, a brief summary of the research papers published in this SI will be presented, with organs-on-a-chip, microfluidic devices for detection, and device optimization having been identified as the main topics.
Autores principais:Carvalho, Violeta Meneses
Outros Autores:Teixeira, Senhorinha F.C.F.; Ribeiro, J.E.
Assunto:Cell culture techniques Microfluidics
Ano:2022
País:Portugal
Tipo de documento:livro
Tipo de acesso:acesso aberto
Instituição associada:Instituto Politécnico de Bragança
Idioma:inglês
Origem:Biblioteca Digital do IPB
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author Carvalho, Violeta Meneses
author2 Teixeira, Senhorinha F.C.F.
Ribeiro, J.E.
author2_role author
author
author_facet Carvalho, Violeta Meneses
Teixeira, Senhorinha F.C.F.
Ribeiro, J.E.
author_role author
contributor_name_str_mv Biblioteca Digital do IPB
country_str PT
creators_json_txt [{\"Person.name\":\"Carvalho, Violeta Meneses\"},{\"Person.name\":\"Teixeira, Senhorinha F.C.F.\"},{\"Person.name\":\"Ribeiro, J.E.\",\"Person.identifier.orcid\":\"0000-0001-6300-148X\"}]
datacite.contributors.contributor.contributorName.fl_str_mv Biblioteca Digital do IPB
datacite.creators.creator.creatorName.fl_str_mv Carvalho, Violeta Meneses
Teixeira, Senhorinha F.C.F.
Ribeiro, J.E.
datacite.date.Accepted.fl_str_mv 2022-01-01T00:00:00Z
datacite.date.available.fl_str_mv 2023-01-05T09:15:16Z
datacite.date.embargoed.fl_str_mv 2023-01-05T09:15:16Z
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datacite.subjects.subject.fl_str_mv Cell culture techniques
Microfluidics
datacite.titles.title.fl_str_mv Micro/nanofluidic and lab-on-a-chip devices for biomedical applications
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.creator.none.fl_str_mv Carvalho, Violeta Meneses
Teixeira, Senhorinha F.C.F.
Ribeiro, J.E.
dc.date.Accepted.fl_str_mv 2022-01-01T00:00:00Z
dc.date.available.fl_str_mv 2023-01-05T09:15:16Z
dc.date.embargoed.fl_str_mv 2023-01-05T09:15:16Z
dc.format.none.fl_str_mv application/pdf
dc.identifier.none.fl_str_mv http://hdl.handle.net/10198/26314
dc.language.none.fl_str_mv eng
dc.publisher.none.fl_str_mv MDPI
dc.rights.cclincense.fl_str_mv http://creativecommons.org/licenses/by/4.0/
dc.rights.none.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.subject.none.fl_str_mv Cell culture techniques
Microfluidics
dc.title.fl_str_mv Micro/nanofluidic and lab-on-a-chip devices for biomedical applications
dc.type.none.fl_str_mv http://purl.org/coar/resource_type/c_2f33
description Micro/Nanofluidic and lab-on-a-chip devices have been increasingly used in biomedical research [1]. Because of their adaptability, feasibility, and cost-efficiency, these devices can revolutionize the future of preclinical technologies. Furthermore, they allow insights into the performance and toxic effects of responsive drug delivery nanocarriers to be obtained, which consequently allow the shortcomings of two/three-dimensional static cultures and animal testing to be overcome and help to reduce drug development costs and time [2–4]. With the constant advancements in biomedical technology, the development of enhanced microfluidic devices has accelerated, and numerous models have been reported. Given the multidisciplinary of this Special Issue (SI), papers on different subjects were published making a total of 14 contributions, 10 original research papers, and 4 review papers. The review paper of Ko et al. [1] provides a comprehensive overview of the significant advancements in engineered organ-on-a-chip research in a general way while in the review presented by Kanabekova and colleagues [2], a thorough analysis of microphysiological platforms used for modeling liver diseases can be found. To get a summary of the numerical models of microfluidic organ-on-a-chip devices developed in recent years, the review presented by Carvalho et al. [5] can be read. On the other hand, Maia et al. [6] report a systematic review of the diagnosis methods developed for COVID-19, providing an overview of the advancements made since the start of the pandemic. In the following, a brief summary of the research papers published in this SI will be presented, with organs-on-a-chip, microfluidic devices for detection, and device optimization having been identified as the main topics.
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person_str_mv Carvalho, Violeta Meneses
Teixeira, Senhorinha F.C.F.
Ribeiro, J.E.
Ribeiro, J.E.
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spelling engMDPIpt_PTMicro/Nanofluidic and lab-on-a-chip devices have been increasingly used in biomedical research [1]. Because of their adaptability, feasibility, and cost-efficiency, these devices can revolutionize the future of preclinical technologies. Furthermore, they allow insights into the performance and toxic effects of responsive drug delivery nanocarriers to be obtained, which consequently allow the shortcomings of two/three-dimensional static cultures and animal testing to be overcome and help to reduce drug development costs and time [2–4]. With the constant advancements in biomedical technology, the development of enhanced microfluidic devices has accelerated, and numerous models have been reported. Given the multidisciplinary of this Special Issue (SI), papers on different subjects were published making a total of 14 contributions, 10 original research papers, and 4 review papers. The review paper of Ko et al. [1] provides a comprehensive overview of the significant advancements in engineered organ-on-a-chip research in a general way while in the review presented by Kanabekova and colleagues [2], a thorough analysis of microphysiological platforms used for modeling liver diseases can be found. To get a summary of the numerical models of microfluidic organ-on-a-chip devices developed in recent years, the review presented by Carvalho et al. [5] can be read. On the other hand, Maia et al. [6] report a systematic review of the diagnosis methods developed for COVID-19, providing an overview of the advancements made since the start of the pandemic. In the following, a brief summary of the research papers published in this SI will be presented, with organs-on-a-chip, microfluidic devices for detection, and device optimization having been identified as the main topics.application/pdfpt_PTMicro/nanofluidic and lab-on-a-chip devices for biomedical applicationsCarvalho, Violeta MenesesTeixeira, Senhorinha F.C.F.PersonalRibeiro, J.E.DSpacehttp://dspace.org/items/c90169e6-7889-4270-a096-35b98c75f9f9DSpacehttp://dspace.org/items/c90169e6-7889-4270-a096-35b98c75f9f9RibeiroJ.E.Ciência IDhttps://www.ciencia-id.pt0F15-FB62-29DBORCIDhttp://orcid.org0000-0001-6300-148XResearcher IDhttps://www.researcherid.comG-3839-2018Scopus Author IDhttps://www.scopus.com25638652400HostingInstitutionOrganizationalBiblioteca Digital do IPBe-mailmailto:dspace@ipb.ptdspace@ipb.ptISBNIsPartOf978-3-0365-6099-1ISSNIsPartOf978-3-0365-6100-4DOIIsPartOf10.3390/books978-3-0365-6099-12023-01-05T09:15:16Z20222022-01-01T00:00:00ZHandlehttp://hdl.handle.net/10198/26314http://purl.org/coar/access_right/c_abf2open accessCell culture techniquesMicrofluidics50219222 bytesliteraturehttp://purl.org/coar/resource_type/c_2f33book2022http://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_abf2application/pdffulltexthttps://bibliotecadigital.ipb.pt/bitstreams/5dfd7c37-a0ce-4e41-b74d-5068956b578a/downloadMicro/nanofluidic and lab-on-a-chip devices for biomedical applicationsBasel
spellingShingle Micro/nanofluidic and lab-on-a-chip devices for biomedical applications
Carvalho, Violeta Meneses
Cell culture techniques
Microfluidics
status SINGLETON
subject.fl_str_mv Cell culture techniques
Microfluidics
title Micro/nanofluidic and lab-on-a-chip devices for biomedical applications
title_full Micro/nanofluidic and lab-on-a-chip devices for biomedical applications
title_fullStr Micro/nanofluidic and lab-on-a-chip devices for biomedical applications
title_full_unstemmed Micro/nanofluidic and lab-on-a-chip devices for biomedical applications
title_short Micro/nanofluidic and lab-on-a-chip devices for biomedical applications
title_sort Micro/nanofluidic and lab-on-a-chip devices for biomedical applications
topic Cell culture techniques
Microfluidics
topic_facet Cell culture techniques
Microfluidics
url http://hdl.handle.net/10198/26314
visible 1